Baseline clinical and radiological patient characteristics
| All patients N=100 | Solumbra group N=55 (%) | ADAPT group N=45 (%) | p Value* | |
|---|---|---|---|---|
| Mean age, years | 68 | 69.6 | 66.1 | 0.16 |
| Sex | 0.05 | |||
| Female | 49 | 32 (58) | 17 (38) | |
| Male | 51 | 23 (42) | 28 (62) | |
| Atrial fibrillation | 43 | 28 (51) | 15 (33) | 0.11 |
| Diabetes mellitus | 24 | 16 (29) | 8 (18) | 0.24 |
| Hypertension | 63 | 39 (71) | 24 (53) | 0.1 |
| Mean NIHSS | 17.9 | 16.8 | 19.2 | 0.02 |
| IV-tPA administration | 58 | 33 (60) | 25 (56) | 0.69 |
| Mean baseline NCCT ASPECTS | 8.6 | 8.2 | 9.1 | <0.01 |
| CT angiography | 73 | 44 (80) | 29 (64) | 0.11 |
| Thrombus location | ||||
| ICA terminus | 30 | 11 (20) | 19 (42) | 0.03 |
| MCA M1 | 57 | 36 (66) | 21 (47) | 0.07 |
| MCA M2 | 9 | 6 (11) | 3 (7) | 0.5 |
| MCA M3 | 4 | 2 (4) | 2 (4) | 1 |
| Left side | 55 | 27 (49) | 28 (62) | 0.23 |
| Tandem ICA origin occlusion | 17 | 8 (15) | 9 (20) | 0.6 |
| Mean cervical tortuosity, degrees | 219 | 196 | 248 | 0.1 |
| Severe, ≥360° | 23 | 8 (15) | 15 (33) | 0.03 |
| Mean time from LKW to puncture, min | 248 | 267 | 224 | 0.08 |
Bold type indicates statistical significance.
*p Value for the difference between the Solumbra group and the ADAPT group using either the Student t test or Fisher exact test.
ADAPT, A Direct Aspiration first-Pass Thrombectomy; ASPECTS, Alberta Stroke Program Early CT Score; ICA, internal carotid artery; IV-tPA, intravenous tissue plasminogen activator; LKW, last known well; MCA, middle cerebral artery; N, number of patients; NCCT, non-contrast CT; NIHSS, National Institutes of Health Stroke Scale.