Presenting symptoms in all patient who underwent bilateral inferior petrosal sinus sampling
| Symptom | Percentage of patients |
|---|---|
| Weight gain (typically central) | 85 |
| Moon facies | 76 |
| Skin changes (stria, acne, bruising, slow wound healing) | 49 |
| Sex hormone changes (irregular menses, hirsutism, decreased libido) | 41 |
| Hypertension and/or diabetes | 37 |
| Muscle and bone weakness (pain, osteoporosis, fractures, atrophy) | 34 |
| Fatigue | 25 |
| Mood and cognitive changes (irritability, anxiety, depression, insomnia, memory loss) | 24 |
| Hair loss | 9 |
| Visual impairment | 4 |
| Weight loss | 2 |
| Asymptomatic | <1 |