TableĀ 1

Presenting symptoms in all patient who underwent bilateral inferior petrosal sinus sampling

SymptomPercentage of patients
Weight gain (typically central)85
Moon facies76
Skin changes (stria, acne, bruising, slow wound healing)49
Sex hormone changes (irregular menses, hirsutism, decreased libido)41
Hypertension and/or diabetes37
Muscle and bone weakness (pain, osteoporosis, fractures, atrophy)34
Mood and cognitive changes (irritability, anxiety, depression, insomnia, memory loss)24
Hair loss9
Visual impairment4
Weight loss2