Characteristics | Patients with MT and IVT (n=105) | Patients with MT and no IVT (n=145) | p Value | Patients with MT alone without contraindications for IVT (n=70) | Patients with MT alone with contraindications for IVT (n=75) | p Value |
---|---|---|---|---|---|---|
Age (years) median (SD) | 70.2 (12.6) | 69.3 (14.9) | 0.882 | 70.7 (17.1) | 68 (12.4) | 0.041 |
Male sex, n (%) | 52 (49.5) | 78 (53.8) | 0.469 | 38 (54.3) | 40 (54.1) | 0.978 |
NIHSS score at admission, median (IQR) | 15.5 (12–20) | 15 (9–19) | 0.215 | 15 (10–18) | 15 (8–20) | 0.683 |
Secondarily referred for thrombectomy, n (%) | 103 (98.1) | 100 (69.0) | <0.001 | 41 (58.6) | 59 (78.7) | 0.009 |
Hypertension, n (%) | 82 (79.6) | 104 (71.7) | 0.157 | 49 (70.0) | 55 (73.3) | 0.656 |
Diabetes mellitus, n (%) | 16 (16.7) | 28 (19.9) | 0.527 | 11 (16.4) | 17 (23.0) | 0.330 |
Current smoking, n (%) | 15 (15.2) | 25 (18.0) | 0.564 | 12 (17.9) | 13 (18.1) | 0.982 |
Hyperlipidemia, n (%) | 17 (17.0) | 31 (22.1) | 0.326 | 13 (19.4) | 18 (24.7) | 0.454 |
Atrial fibrillation, n (%) | 26 (25.5) | 56 (38.9) | 0.028 | 25 (36.2) | 31 (41.3) | 0.530 |
Prior cerebrovascular event, n (%) | 13 (12.9) | 34 (23.8) | 0.033 | 14 (20.3) | 20 (27.0) | 0.344 |
Symptom-to-first imaging time* (min), median (IQR) | 77 (55–139) | 87 (57–172) | 0.516 | 73 (55–119) | 119 (59–369) | 0.001 |
Symptom-to-needle time* (min), median (IQR) | 115 (84–181) | |||||
Site of symptomatic vessel occlusion†, n (%) | ||||||
Internal carotid artery | 19 (18.1) | 30 (20.7) | 0.610 | 20 (28.6) | 10 (13.3) | 0.024 |
Carotid T | 21 (20.0) | 20 (13.8) | 0.191 | 6 (8.6) | 14 (18.7) | 0.078 |
MCA M1 | 48 (45.7) | 52 (35.9) | 0.117 | 25 (35.7) | 27 (36.0) | 0.971 |
MCA M2 | 20 (19.0) | 23 (15.9) | 0.510 | 12 (17.1) | 11 (14.7) | 0.683 |
Basilar artery | 10 (9.5) | 21 (14.5) | 0.240 | 7 (10.0) | 14 (18.7) | 0.138 |
Other (ACA A1. PCA P1. vertebral artery) | 6 (5.7) | 14 (9.7) | 0.257 | 4 (5.7) | 10 (13.3) | 0.121 |
*Stroke symptom onset or last time point patient seen well.
†Multiple occlusion sites possible.ACA, anterior cerebral artery; IVT, intravenous thrombolysis; MCA, middle cerebral artery; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; PCA, posterior cerebral artery.