Table 3

Treatment details, complications and clinical outcome

Patients with MT and IVT (n=105)Patients with MT and no IVT (n=145)p ValuePatients with MT alone without contraindications for IVT (n=70)Patients with MT alone with contraindications for IVT (n=75)p Value
Symptom-to-groin puncture-time* (min), median (IQR)233 (198–295)210 (152–330)0.103183 (132–225)271 (177–543)<0.001
First imaging-to-groin puncture time (min), median (IQR)148 (122–167)112 (60–153)<0.00185 (51–141)131 (89–164)0.022
Symptom-to-end-of-thrombectomy time*, (min), median (IQR)280 (233–370)272 (193–401)0.221231 (169–296)325 (323–672)<0.001
Successful recanalization (TICI score 2b/3), n (%)76 (73.8)106 (73.1)0.95252 (74.3)54 (74)0.966
Number of passes of the thrombectomy device, median (min–max)1 (1–11)2 (0–9)0.9042.0 (0–9)2.0 (1–9)0.605
Embolus in further vessel territory, n (%)6 (5.7)5 (3.4)0.3742 (2.9)3 (4.0)0.684
Iatrogenic vessel dissection, n (%)7 (6.7)4 (2.8)0.2383 (4.3)1 (1.3)0.304
Subarachnoidal hemorrhage, n (%)3 (2.9)4 (2.8)0.9471 (1.4)3 (4.0)0.331
Groin hematoma, n (%)2 (1.9)2 (1.4)0.7321 (1.4)1 (1.3)0.976
Symptomatic ICH, n (%)6 (5.9)5 (3.5)0.3872 (2.9)3 (4.1)0.708
Any ICH†, n (%)18 (17.6)22 (15.6)0.6719 (13.2)13 (17.3)0.455
Favorable outcome (mRS 0–2) at follow-up, n (%)37 (35.2)58 (40.0)0.44434 (48.6)24 (32.0)0.042
Mortality at follow-up, n (%)28 (26.7)46 (31.7)0.338718 (25.7)28 (37.3)0.133
  • *Stroke symptom onset or last time point patient seen well.

  • †Including both asymptomatic and symptomatic ICH.

  • ICH, intracranial hemorrhage; IVT, intravenous thrombolysis; MT, mechanical thrombectomy; mRS, modified Rankin Scale; TICI, Thrombolysis in Cerebral Infarction Score.