Contraindications for bridging IVT
| Contraindication | No. of patients (%) (n=75) |
|---|---|
| Wake-up stroke or >4.5 h after known stroke symptom onset | 30 (40) |
| Effective anticoagulation (INR >1.7 or full-dose heparin/LMWH or NOAC) | 16 (21.3) |
| Recent surgery | 4 (5.3) |
| Recent stroke | 4 (5.3) |
| History of ICH | 2 (2.7) |
| Other reasons (pancreatitis, sepsis, tumor, severe cerebral microangiopathy, advanced age) | 12 (16) |
| Multiple reasons | 7 (9.3) |
ICH, intracranial hemorrhage; INR, international normalized ratio; IVT, intravenous thrombolysis; LMWH, low-molecular-weight heparin; NOAC, new oral anticoagulant.