Table 2

Contraindications for bridging IVT

ContraindicationNo. of patients (%) (n=75)
Wake-up stroke or >4.5 h after known stroke symptom onset30 (40)
Effective anticoagulation (INR >1.7 or full-dose heparin/LMWH or NOAC)16 (21.3)
Recent surgery4 (5.3)
Recent stroke4 (5.3)
History of ICH2 (2.7)
Other reasons (pancreatitis, sepsis, tumor, severe cerebral microangiopathy, advanced age)12 (16)
Multiple reasons7 (9.3)
  • ICH, intracranial hemorrhage; INR, international normalized ratio; IVT, intravenous thrombolysis; LMWH, low-molecular-weight heparin; NOAC, new oral anticoagulant.