Demographic and baseline characteristics and outcome variables of patients with proximal and distal occlusions by device selection
| ICA and proximal M1 | Distal M1 and M2 | |||||
|---|---|---|---|---|---|---|
| Characteristic | TREVO (n=27) | Capture LP (n=15) | p1Value | TREVO (n=15) | Capture LP (n=28) | p2Value |
| Age (years), mean (SD) | 65.5 (14.0) | 60.3 (9.3) | 0.20 | 71.2 (10.0) | 66.3 (10.5) | 0.15 |
| Male sex (%) | 13 (48) | 10 (67) | 0.24 | 7 (47) | 16 (57) | 0.51 |
| NIHSS before treatment, median (IQR) | 16 (7) | 14 (5) | 0.87 | 15 (5) | 13.5 (9) | 0.31 |
| ASPECTS score at admission NCCT, median (IQR) | 8 (4) | 8 (3) | 0.81 | 10 (3) | 9 (2) | 0.96 |
| ASPECTS score at admission MTT, median (IQR) | 1 (2) | 1 (2) | 0.63 | 3 (3) | 4 (5) | 0.14 |
| ASPECTS score at admission CBV, median (IQR) | 5.5 (5) | 8 (6) | 0.24 | 8 (3) | 9 (4) | 0.66 |
| Onset to imaging time (min), mean (SD) | 159 (104) | 143 (77) | 0.62 | 137 (92) | 152 (112) | 0.65 |
| Clot burden sore, median (IQR) | 4 (3) | 5 (3) | 0.63 | 6 (2) | 8 (3) | 0.08 |
| Collateral score, median (IQR) | 1 (2) | 1 (2) | 0.36 | 1 (3) | 2 (2) | 0.11 |
| Hypertension n (%) | 15 (56) | 7 (47) | 0.58 | 5 (33) | 10 (36) | 0.88 |
| Diabetes n (%) | 4 (15) | 2 (13) | 0.90 | 5 (33) | 4 (14) | 0.14 |
| Atrial fibrillation n (%) | 12 (44) | 8 (53) | 0.56 | 11 (73) | 13 (46) | 0.09 |
| Coronary artery disease n (%) | 4 (15) | 2 (13) | 0.90 | 5 (33) | 3 (11) | 0.07 |
| 3-month modified Rankin Scale 0–2 (%) | 15 (58) | 10 (67) | 0.57 | 8 (53) | 17 (61) | 0.64 |
| 3-month modified Rankin Scale 0–1 (%) | 10 (39) | 9 (60) | 0.18 | 3 (20) | 12 (57) | 0.19 |
| 3-month mortality (%) | 4 (15) | 1 (7) | 0.64 | 3 (20) | 1 (4) | 0.11 |
| ASPECTS score at 24 hours CT, median (IQR) | 8 (5) | 8 (2) | 0.92 | 8 (6) | 9 (2) | 0.04 |
| Total infarct volume at 24 hours (ccm), median (SD) | 4.7 (47) | 2.8 (43) | 0.90 | 10.5 (101) | 1.2 (13.4) | 0.04 |
| Onset to recanalization time (min), mean (SD) | 238 (106) | 239 (88) | 0.97 | 213 (76) | 245 (121) | 0.38 |
| TICI 2b or 3 (%) | 26 (96) | 13 (87) | 0.25 | 13 (87) | 25 (89) | 0.80 |
| Duration of the intervention (min), mean (SD) | 31 (24) | 32 (25) | 0.87 | 38 (25) | 32 (16) | 0.38 |
| Hemorrhagic complication at 24 hours (%) | 5 (20) | 4 (27) | 0.71 | 5 (33) | 2 (7) | 0.04 |
| Major space-occupying effect (PH2 or PHr2, %) | 0 (0) | 1 (7) | 0.38 | 2 (20) | 0 (0) | 0.04 |
| Post-infarct edema COED2 or COED3 | 5 (20) | 2 (13) | 0.69 | 5 (33) | 2 (7) | 0.04 |
p1=p value between TREVO and Capture LP proximal occlusion groups; p2=p value between TREVO and Capture LP distal occlusion groups.
ASPECTS, Alberta Stroke Program Early CT Score; CBV, cerebral blood volume; ICA, internal carotid artery; MTT, mean transit time; NIHSS, National Institutes of Health Stroke Scale; TICI, Thrombolysis In Cerebral Infarction.