Baseline characteristics of the cohort as stratified by age
| Variable | Age <90 (n=175) | Age ≥90 (n=18) | p Value |
|---|---|---|---|
| Age (years), mean (SD) | 68.4 (±13.7) | 91.9 (±2.3) | |
| Female | 75 (43) | 11 (61) | 0.212 |
| Hypertension | 139 (79.4) | 15 (83.3) | 0.999 |
| Hyperlipidemia | 101 (57.7) | 10 (55.6) | 0.999 |
| Atrial fibrillation | 63 (36) | 13 (72.2) | 0.004 |
| IV tPA | 84 (48) | 12 (66.7) | 0.146 |
| NIHSS, mean (SD) | 16.92 (6.27) | 18.28 (5.44) | 0.379 |
| Pre-stroke mRS (CI) | 0.24 (0.17 to 0.35) | 0.77 (0.44 to 1.28) | 0.005 |
| mRS 0 | 130 | 5 | |
| mRS 1 | 24 | 8 | |
| mRS 2 | 9 | 4 | |
| mRS 3 | 12 | 1 | |
| Location of arterial occlusion | |||
| Internal carotid artery | 51 (29.1) | 6 (33.3) | 0.920 |
| Middle cerebral artery | 109 (62.3) | 12 (66.7) | 0.910 |
| Basilar artery | 8 (4.6) | 0 (0.0) | 0.999 |
| Others | 7 (4.0) | 0 (0.0) | 0.999 |
| Complete recanalization* | 109 (62.3) | 12 (66.7) | 0.999 |
| Infarct volume (mL), (CI) | 84 (68 to 104) | 130 (83 to 203) | 0.0832 |
| Parenchymal hemorrhage† | 46 (26.3) | 6 (33.3) | 0.579 |
| mRS 3–6 at 90 days | 91 (52) | 16 (88.9) | 0.0027 |
| mRS 4–6 at 90 days | 73 (41.7) | 14 (77.8) | 0.006 |
Data are n (%) unless stated otherwise.
*Defined as TICI 2b and 3.
†Defined as PH1 and PH2.
mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; PH, parenchymal hemorrhage type 1 (PH1) and 2 (PH2); tPA, recombinant tissue plasminogen activator; TICI, Thrombolysis In Cerebral Infarction.