Arterial wall alterations
| Arterial model | Endothelial damage | Damage to the internal elastic lamina | Damage to the tunica media/adventitia | Electron microscopy |
|---|---|---|---|---|
| ICAADAPT | No | No | + (some degeneration of medial/adventitial elastic fibers) | Parietal laceration due to manipulation |
| M1ADAPT | + (discontinuous endothelial layer/granulocyte infiltration) | No | ++ (some alterations of medial/adventitial elastic fibers) | Normal endothelial layer with morphological alterations |
| ICACONTROL | Discontinuous endothelium | No | No | Areas with and without endothelial cells |
| M1CONTROL | No | No | No | No |
| ICASR | +++ (endothelial layer absent) | +++ (thickened) | +++ (some alterations of medial/adventitial elastic fibers) | Pronounced alterations of the elastic layer of the tunica media |
| M1SR | +++ (endothelial layer absent) | +++ (thickened) | +++ (some alterations of medial/adventitial elastic fibers) | Endothelial layer absent |
See text for description of the arterial models.
ADAPT, a direct aspiration first pass technique; ICA, internal carotid artery; SR, stent retriever.