Baseline characteristics of patients with BAO with regard to outcome
| Characteristics | Overall (n=51) | Poor outcome 3-month mRS 3–6 (n=38) | Favorable outcome 3-month mRS 0–2 (n=13) | p Value |
|---|---|---|---|---|
| Age, years, median (IQR) | 72 (66–78) | 71 (66–80) | 73 (67–74) | 0.72 |
| Men, n (%) | 36 (70.6) | 28 (73.7) | 8 (61.5) | 0.49 |
| Baseline NIHSS score, median (IQR) | 18 (11–23) | 18 (16–23) | 15 (9–19) | 0.04 |
| Site of occlusion | ||||
| Proximal BA, n (%) | 10 (19.6) | 9 (23.7) | 1 (7.7) | 0.42 |
| Mid BA, n (%) | 21 (41.2) | 16 (42.1) | 5 (38.5) | 1.00 |
| Top of BA, n (%) | 20 (39.2) | 13 (34.2) | 7 (53.8) | 0.32 |
| Thrombus length, mm, median (IQR) | 7.5 (5–14.4) | 8.3 (6–15.6) | 7.3 (4.9–10.3) | 0.23 |
| Density, absolute HU | 51.6±6.2 | 50.1±6.1 | 55.7±4.3 | 0.004 |
| Density, relative HU | 1.34±0.15 | 1.28±0.12 | 1.49±0.12 | <0.001 |
| HDBA sign, n (%) | 42 (82.4) | 29 (76.3) | 13 (100) | 0.09 |
| Onset-to-treatment, min, median (IQR) | 222 (178–462) | 221 (183–479) | 244 (175–515) | 0.90 |
| Strategy of EVT | ||||
| IA rtPA only, n (%) | 5 (9.6) | 5 (12.8) | 0 (0) | 0.31 |
| Mechanical only, n (%) | 30 (57.7) | 22 (56.4) | 8 (61.5) | 1.00 |
| Mechanical+IA rtPA, n (%) | 16 (32.7) | 12 (30.8) | 5 (38.5) | 0.73 |
| Etiology | ||||
| Cardioembolic, n (%) | 30 (58.8) | 23 (60.5) | 7 (53.8) | 0.75 |
| Large artery atherosclerotic, n (%) | 13 (25.5) | 9 (23.7) | 4 (30.8) | 0.72 |
| Other confirmed etiology, n (%) | 5 (9.8) | 4 (10.5) | 1 (7.7) | 1.00 |
| Unknown, n (%) | 3 (5.9) | 2 (5.3) | 1 (7.7) | 1.00 |
| sICH per ECASS II, n (%) | 5 (9.8) | 5 (13.2) | 0 | 0.31 |
| Recanalization, TIMI 2–3, n (%) | 41 (80.4) | 29 (76.3) | 12 (92.3) | 0.42 |
Bold type indicates statistical significance.
BA, basilar artery; BAO, basilar artery occlusion; ECASS, European Cooperative Acute Stroke Study; EVT, endovascular therapy; HDBA, hyperdense basilar artery; HU, Hounsfield units; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale score; rtPA, recombinant tissue plasminogen activator; sICH, symptomatic intracranial hemorrhage; TIMI, Thrombolysis in Myocardial Infarction.