Comparison of outcomes after MT in patients with and without medical contraindications for IVT
| Outcome | MT (N=21) | IVT +MT (N=53) | p Value |
|---|---|---|---|
| Duration of endovascular procedure, min, median (IQR) | 69 (47–117) | 60 (40–84) | 0.27 |
| Time from symptom onset to recanalization, min, median (IQR) | 259 (215– 328) | 325 (280–390) | 0.018 |
| NIHSS at 24 hours, median (IQR) | 8 (5–16) | 5 (2–13) | 0.15 |
| NIHSS at 7 days, median (IQR) | 5 (2–16) | 3 (1–10) | 0.2 |
| Significant improvement at 7 days, N (%) | 12 (57) | 33 (62) | 0.68 |
| NIHSS score 0–1 7 days, N (%) | 5 (24) | 19 (36) | 0.31 |
| Mortality within 7 days, N (%) | 1 (5) | 2 (4) | 0.9 |
| Symptomatic intracranial hemorrhage, N (%) | 0 (0) | 3 (6) | 0.54 |
| Any intracranial hemorrhage, N (%) | 2 (10) | 13 (25) | 0.2 |
| HI1 | 0 (0) | 4 (7.5) | |
| HI2 | 1 (5) | 3 (6) | |
| PH1 | 1 (5) | 2 (4) | |
| PH2 | 0 (0) | 4 (7.5) | |
| Independence (mRS 0–2) at 3 months, N (%) | 9 (43) | 36 (68) | 0.046 |
| Mortality at 3 months, N (%) | 3 (14) | 2 (4) | 0.13 |
| Death or dependence at 3 months, N (%) | 12 (57) | 17 (32) | 0.04 |
HI, hemorrhagic infarction; IVT, IV thrombolysis; mRS, modified Rankin Scale; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; PH, parenchymal hematoma.