Demographic characteristics of the two patient groups
| Traditional (n=57) | CAPTIVE (n=39) | p Value | |
|---|---|---|---|
| Demographics and workflow | |||
| Age, years (median (IQR)) | 78 (67–89) | 77 (62–84) | 0.2324 |
| Female (%) | 61 (35/57) | 46 (18/39) | 0.1400 |
| Diabetes (%) | 28.1 (16/57) | 10.3 (4/39) | 0.0421 |
| Atrial fibrillation/atrial flutter (%) | 66.7 (38/57) | 59.0 (23/39) | 0.5191 |
| Hypertension (%) | 77.2 (44/57) | 61.5 (24/39) | 0.1136 |
| NIHSS score (median (IQR)) | 19 (15–22) | 19 (14–23) | 0.7999 |
| NCCT ASPECTS (median (IQR)) | 10 (9–10) | 10 (8–10) | 0.5925 |
| IV tPA given (%) | 68.4 (39/57) | 43.5 (17/39) | 0.0154 |
| Site of occlusion | |||
| Left hemisphere involved (%) | 58 (33/57) | 52 (20/39) | 0.5222 |
| ICA occlusion (%) | 21 (12/57) | 13 (5/39) | 0.2994 |
| M1 occlusion (%) | 79 (45/57) | 87 (34/39) | |
| Time intervals | |||
| Symptom onset to NCCT, min (median (95% CI)) | 71 (57 to 102) | 81 (52 to 256) | 0.5206 |
| Symptom onset to angiography, min (median (95% CI)) | 195 (160 to 209) | 184 (145 to 321) | 0.4424 |
| NCCT to angiography, min (median (95% CI)) | 104 (80 to121) | 99 (79 to 110) | 0.4849 |
| CTA to angiography (median (95% CI)) | 83 (61 to 100) | 81 (66 to 100) | 0.9659 |
| Angiographic outcomes | |||
| Groin puncture to recanalization, min (median (95% CI)) | 31 (23 to 44) | 14 (12 to 28) | 0.0001 |
| Number of passes (mean (95% CI)) | 1.9 (1.6 to 2.3) | 1.7 (1.4 to 2.1) | 0.3729 |
| Single pass recanalization | 49.1% (28/57) | 59.0% (23/39) | 0.3421 |
| Recanalization (mTICI classification) | N/A | ||
| mTICI 0/1 | 2% (1/57) | 0% (0/39) | |
| mTICI 2a | 18% (10/57) | 0% (0/39) | |
| mTICI 2b | 40% (23/57) | 21% (8/39) | |
| mTICI 2c | 23% (13/57) | 46% (18/39) | |
| mTICI 3 | 17% (10/57) | 33% (13/39) | |
| Total mTICI 2b/2c/3 | 46/57 | 39/39 | N/A |
| Total mTICI 2c/3 | 40% (23/57) | 79.5% (31/39) | <0.0001 |
| Embolization to new territory | 11% (6/53) | 5% (2/39) | 0.2976 |
Bold type indicates statistical significance.
ASPECTS, Alberta Stroke Program Early CT Score; CTA, CAPTIVE, continuous aspiration prior to intracranial vascular embolectomy; CT angiography; ICA, internal carotid artery; mTICI, modified Thrombolysis in Cerebral Ischemia; NCCT, non-contrast CT scan; NIHSS, National Institute of Health Stroke Scale; tPA, tissue plasminogen activator.