Multivariate logistic regression analysis showing relationship of distance traveled to outcomes among transferred patients treated at a single center
| Variable | OR (95% CI) | p Value |
|---|---|---|
| Intracerebral hemorrhage | ||
| IV tPA+distance | ||
| IV tPA | 0.97 (0.20 to 4.89) | 0.965 |
| Distance | 1.07 (0.85 to 1.31) | 0.525 |
| Time to intervention+distance | ||
| Time to intervention | 1.03 (1.00 to 1.05)* | 0.042 |
| Distance | 1.11 (0.95 to 1.29)* | 0.184 |
| ASPECTS+distance | ||
| ASPECTS | 0.61 (0.31 to 1.14) | 0.120 |
| Distance | 1.00 (0.98 to 1.02) | 0.804 |
| TICI ≥2b+distance | ||
| TICI ≥2b | 2.87 (1.66 to 9.01) | 0.009 |
| Distance | 1.15 (0.98 to 1.36)* | 0.077 |
| Death | ||
| Age+distance | ||
| Age | 1.09 (1.03 to 1.18)* | 0.001 |
| Distance | 1.29 (1.08 to 1.61)* | 0.004 |
| NIHSS+distance | ||
| NIHSS | 1.06 (0.95 to 1.20)* | 0.304 |
| Distance | 1.23 (1.03 to 1.51)* | 0.017 |
| Basilar+distance | ||
| Basilar | 6.07 (0.90 to 41.60) | 0.063 |
| Distance | 1.27 (1.07 to 1.56)* | 0.005 |
| IV tPA+distance | ||
| IV tPA | 1.13 (0.32 to 4.16) | 0.852 |
| Distance | 1.02 (1.01 to 1.05) | 0.014 |
| Time to intervention+distance | ||
| Time to intervention | 0.99 (0.95 to 1.02) | 0.467 |
| Distance | 1.26 (1.07 to 1.54) | 0.006 |
| ASPECTS+distance | ||
| ASPECTS | 1.31 (0.77 to 2.36) | 0.327 |
| Distance | 1.29 (1.08 to 1.59) | 0.004 |
| TICI ≥2b+distance | ||
| TICI ≥2b | 2.33 (0.62 to 8.42) | 0.205 |
| Distance | 1.25 (1.06 to 1.54)* | 0.009 |
| 90-Day mRS >2 | ||
| Age | 1.02 (0.99 to 1.07) | 0.225 |
| Distance | 1.09 (0.89 to 1.41) | 0.424 |
| NIHSS | 1.15 (1.00 to 1.36) | 0.044 |
| Dominant | 1.45 (0.39 to 5.32) | 0.572 |
| IV tPA | 1.35 (0.32 to 5.77) | 0.680 |
| Time to Intervention | 1.02 (0.99 to 1.06) | 0.171 |
| ASPECTS | 0.95 (0.54 to 1.69) | 0.862 |
| TICI ≥2b | 0.11 (0.01 to 0.58) | 0.007 |
| Intracerebral hemorrhage | 4.31 (0.43 to 112.70) | 0.231 |
Significant p values are shown in bold.
*Unit OR, indicating the increase in OR for every 1 unit increase in age, NIHSS, and ASPECTS and every 10 mile increase in distance traveled.
ASPECTS, Alberta Stroke Program Early CT Score; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; TICI, Thrombolysis in Cerebral Infarction; tPA, tissue plasminogen activator.