Embolization characteristics and embolization extent
| Study group | PHIL | Onyx | p Value*PHIL vs Onyx | ||
| Subgroup | PHIL_30s | PHIL_60s | Onyx_30s | Onyx_60s | p Value†subgroups |
| Total procedure time, s | 425 (292; 548) | 376 (248; 589) | 0.645 | ||
| 282 (259; 319) | 609 (485; 795) | 243 (228; 334) | 553 (433; 669) | 0.052 | |
| Total injection time, s | 66 (62; 75) | 74 (68; 118) | 0.398 | ||
| 64 (61; 67) | 78 (65; 99) | 67 (59; 90) | 93 (74; 118) | 0.320 | |
| Time per single injection, s | 7.9 (6.9; 9.5) | 9.6 (8.7; 10.3) | 0.079 | ||
| 6.8 (6.6; 7.6) | 9.2 (8.1; 10.5) | 10.2 (9.9; 10.3) | 8.6 (8.2; 13.6) | 0.099 | |
| Injections, n | 9 (8; 11) | 8 (6; 11) | 0.314 | ||
| 9 (8; 10) | 10 (8; 12) | 7 (6; 9) | 9 (7; 11) | 0.599 | |
| Volume of LEA per procedure, mL | 0.15 (0.14; 0.25) | 0.45 (0.41; 0.46) | <0.001 | ||
| 0.13 (0.10; 0.15) | 0.25 (0.23; 0.28) | 0.38 (0.30; 0.45) | 0.48 (0.45; 0.61) | <0.001 | |
| Embolization extent‡, % | 44 (25; 69) | 69 (43; 88) | 0.101 | ||
| 24 (23; 28) | 72 (62; 82) | 73 (54; 88) | 62 (42; 82) | 0.035§PHIL_30s versus PHIL_60s | |
*Mann–Whitney test.
†Kruskal–Wallis test with post-hoc Dunn’s test.
‡Determined using pre-interventional angiography and post-interventional x-ray (see also figure 1E and F)
§Adjusted p value of post-hoc Dunn’s test.
LEA, liquid embolic agent; Onyx, Onyx 18 ; PHIL, PHIL 25; data presented as median (lower quartile; upper quartile).