Participating centers and number of procedures
| Center | Stroke center designation | No of operators | No of hospitals | Total no of procedures |
| Wake Forest University, Baptist Hospital Winston-Salem, NC | Comprehensive | 3 | 1 | 17 |
| Medical University of South Carolina Charleston, SC | Comprehensive | 5 | 1 | 45 |
| Barrow Neurological Institute Phoenix, AZ | Primary | 2 | 1 | 10 |
| Baylor College of Medicine Houston, TX | Comprehensive | 2 | 2 | 10 |
| University of South Florida Tampa, FL | Comprehensive | 2 | 1 | 13 |
| Mount Sinai Hospital New York, NY | Comprehensive | 3 | 3 | 23 |
| University of Arizona Tucson, AZ | Primary | 1 | 1 | 8 |
| West Virginia University Morgantown, WV | Comprehensive | 2 | 1 | 16 |
| Massachusetts General Hospital Boston, MA | Comprehensive | 3 | 1 | 14 |
| University of Tennessee Memphis, TN | Comprehensive | 5 | 1 | 39 |