Characteristics | ICAS group (n=47) | Embolic group (n=93) | P value |
Age (years), median (IQR) | 60 (52–67) | 66 (58–74) | 0.014* |
Male | 35 (74.5) | 51 (54.8) | 0.024* |
Hypertension | 29 (61.7) | 50 (53.8) | 0.371 |
Diabetes mellitus | 6 (12.8) | 8 (8.6) | 0.552 |
Hyperlipidemia | 2 (4.3) | 5 (5.4) | 1.000 |
Atrial fibrillation | 12 (25.5) | 46 (49.5) | 0.007* |
Smoke | 22 (46.8) | 38 (40.9) | 0.502 |
NIHSS score, median (IQR) | 14 (12–18) | 17 (14–21) | 0.022* |
ASPECTS, median (IQR) | 9 (8–10) | 9 (9–10) | 0.718 |
Location of occlusion site | 0.241 | ||
ICA | 15 (31.9) | 28 (30.1) | – |
M1 | 28 (59.6) | 47 (50.5) | – |
M2 | 4 (8.5) | 18 (19.4) | – |
IV tPA | 6 (12.8) | 18 (19.4) | 0.329 |
General anesthesia | 19 (40.4) | 24 (25.8) | 0.077 |
Number of stent-retriever passes, median (IQR) | 2 (1–3) | 2 (1–3) | 0.415 |
GP IIb/IIIa inhibitor given | 24 (51.1) | 17 (18.3) | 0.000* |
Balloon expansion | 17 (36.2) | 0 (0) | 0.000* |
Stent-retriever detachment | 11 (23.4) | 2 (2.2) | 0.000* |
Other stent | 9 (19.1) | 0 (0) | 0.000* |
Proximal stenosis/occlusion | 5 (10.6) | 20 (21.5) | 0.113 |
Onset-to-door time (min), median (IQR) | 148 (75–260) | 123 (68–188) | 0.188 |
Door-to-puncture time (min), median (IQR) | 113 (70–166) | 109 (60–159) | 0.374 |
Puncture-to-recanalization time (min), median (IQR) | 68 (42–112) | 51 (35–81) | 0.020* |
Onset-to-recanalization time (min), median (IQR) | 365 (265–480) | 284 (226–406) | 0.037* |
Results are shown as number (%) unless stated otherwise.
*statistically significant,
ASPECTS, Alberta Stroke Programme Early CT Score; GP, glycoprotein; ICA, internal carotid artery; ICAS, intracranial atherosclerosis; M1, first segment of middle cerebral artery; M2, second segment of middle cerebral artery; NIHSS, National Institute of Health Stroke Scale; tPA, tissue plasminogen activator.