Patient demographics and clinical characteristics: data shown for entire cohort and by recanalization status
| Variable | All patients (n=182) | Sufficient recanalization (TICI 2b–3) (n=100) | Insufficient recanalization (TICI 0–2a) (n=82) | P value |
| Age in years, mean±SD | 63.2±16.3 | 62.1±16.7 | 64.6±15.8 | 0.312 |
| Female, n (%) | 88 (51.7) | 42 (42.0) | 46 (56.1) | 0.068 |
| Hypertension, n (%) | 100 (55.0) | 55 (55.0) | 45 (54.9) | 0.991 |
| Hyperlipidemia, n (%) | 72 (39.6) | 38 (38.0) | 34 (41.5) | 0.626 |
| Coronary artery disease, n (%) | 42 (23.1) | 23 (23.0) | 19 (23.2) | 0.983 |
| Atrial fibrillation, n (%) | 67 (36.8) | 37 (37.0) | 30 (36.6) | 0.951 |
| Diabetes mellitus, n (%) | 37 (20.3) | 20 (20.0) | 17 (20.7) | 0.963 |
| Congestive heart failure, n (%) | 28 (15.4) | 18 (18.0) | 10 (12.2) | 0.282 |
| Current cigarette smoking, n (%) | 33 (18.1) | 23 (23.0) | 10 (12.2) | 0.600 |
| Admission glucose level, mean±SD | 138±61 | 130±57 | 148±64 | 0.054 |
| Admission antiplatelet use, n (%) | 61 (33.5) | 37 (37.0) | 24 (29.3) | 0.272 |
| Admission oral anticoagulation use, n (%) | 37 (20.3) | 21 (21.0) | 16 (19.6) | 0.801 |
| Admission antihypertensive use, n (%) | 100 (55.0) | 55 (55.0) | 45 (54.9) | 0.990 |
| Admission NIHSS, median (IQR) | 16 (10–22) | 16 (10–22) | 16 (10–21) | 0.859 |
| ASPECTS on initial head CT, median (IQR) | 6 (4–9) | 7 (5–10) | 6 (4–8) | 0.013 |
| tPA administered, n (%) | 86 (47.3) | 42 (42.0) | 44 (53.7) | 0.125 |
| Length of IAT in min, mean±SD | 135±66 | 127±70 | 145±60 | 0.067 |
| Second generation stentriever, n (%) | 32 (17.6) | 24 (24.0) | 8 (9.8) | 0.011 |
| Symptomatic intracerebral hemorrhage, n (%) | 25 (13.7) | 10 (10.0) | 15 (18.3) | 0.113 |
| Follow-up mRS, median (IQR) | 4 (1–6) | 2 (1–6) | 4 (2–6) | <0.001 |
| Days from stroke onset to mRS, mean±SD | 176±206 | 187±207 | 159±205 | 0.546 |
ASPECTS, Alberta Stroke Program Early CT Score; IAT, intra-arterial therapies; IQR, interquartile range (25th–75th percentiles); mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; TICI, Thrombolysis in Cerebral Infarction; tPA, tissue plasminogen activator.