Variable | Univariable logistic regression analysis | Multivariable logistic regression analysis* | ||
OR (95% CI) | P value* | OR (95% CI) | P value | |
Age (per 10 year increase) | 0.82 (0.59 to 1.14) | 0.239 | ||
Male gender | 0.86 (0.32 to 2.30) | 0.767 | ||
Black race | 0.88 (0.33 to 2.36) | 0.803 | ||
NIHSS score at admission (per 1 point increase) | 0.85 (0.77 to 0.94) | 0.001 | 0.86 (0.76 to 0.97) | 0.017 |
ASPECTS at baseline (per 1 point increase) | 1.14 (0.78 to 1.67) | 0.486 | ||
Good collaterals | 1.01 (0.29 to 3.52) | 0.991 | ||
Hypertension | 0.96 (0.30 to 3.10) | 0.947 | ||
Diabetes mellitus | 0.80 (0.30 to 2.17) | 0.665 | ||
Hyperlipidemia | 0.85 (0.34 to 2.11) | 0.721 | ||
Atrial fibrillation | 0.79 (0.27 to 2.34) | 0.670 | ||
Coronary artery disease | 0.97 (0.27 to 3.44) | 0.962 | ||
Congestive heart failure | 2.14 (0.60 to 7.65) | 0.240 | ||
Smoking | 0.67 (0.21 to 2.10) | 0.491 | ||
Intravenous thrombolysis | 1.96 (0.67 to 5.72) | 0.218 | ||
Onset to arterial puncture time (per 10 min increase) | 0.98 (0.95 to 1.02) | 0.311 | ||
General anesthesia (vs conscious sedation) | 0.59 (0.20 to 1.72) | 0.331 | ||
Serum glucose at admission (per 10 mg/dL increase) | 1.00 (0.95 to 1.06) | 0.895 | ||
Serum LDL (per 10 mg/dL increase) | 1.02 (0.90 to 1.15) | 0.810 | ||
SBP at admission (per 10 mmHg increase) | 0.83 (0.70 to 1.00) | 0.044 | 0.89 (0.69 to 1.14) | 0.357 |
Mean SBP post MT (per 10 mmHg increase)† | 0.96 (0.70 to 1.31) | 0.795 | ||
Minimum SBP post MT (per 10 mmHg increase)† | 1.31 (1.00 to 1.72) | 0.048 | 1.64 (1.04 to 2.60) | 0.033 |
Maximum SBP post MT per 10 mmHg increase)† | 0.67 (0.51 to 0.87) | 0.003 | 0.55 (0.39 to 0.79) | 0.001 |
DBP at admission (per 10 mmHg increase) | 0.87 (0.67 to 1.13) | 0.299 | ||
Mean DBP post MT (per 10 mmHg increase)† | 0.89 (0.58 to 1.35) | 0.574 | ||
Minimum DBP post MT per 10 mmHg increase)† | 0.94 (0.61 to 1.43) | 0.753 | ||
Maximum DBP post MT per 10 mmHg increase)† | 0.83 (0.64 to 1.08) | 0.160 | ||
Cerebral edema | 0.43 (0.14 to 1.32) | 0.140 |
*Cut-off of P<0.1 was used for selection of candidate variables for inclusion in multivariable logistic regression models.
†During the first 24 hours following the end of mechanical thrombectomy.
ASPECTS, Alberta Stroke Program Early CT score; DBP, diastolic blood pressure; LDL, low density lipoprotein; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure.