Baseline characteristics
| DAWN eligible (>24 hours since TLKW) n=21 | DAWN trial intervention arm n=107 | P values | |
| Age, mean±SD | 65.2±11.1 | 69.4±14.1 | 0.2 |
| Male sex, n (%) | 8 (38%) | 42 (39%) | 0.66 |
| Hypertension, n (%) | 17 (81%) | 83 (78%) | 0.73 |
| Diabetes mellitus, n (%) | 7 (33%) | 26 (24%) | 0.38 |
| Atrial fibrillation, n (%) | 2 (9.5%) | 43 (40%) | 0.007 |
| Presentation of stroke, n (%) | |||
| Wake up | 1 (5%) | 67 (63%) | <0.0001 |
| Unwitnessed | 20 (95%) | 29 (27%) | |
| Witnessed | 0 (0%) | 11 (10%) | |
| Admission NIHSS score | 18.2±5.9 | 17.4±5.1 | 0.52 |
| Occlusion location, n (%) | |||
| Internal carotid artery | 11 (52%) | 22 (21%) | 0.001 |
| Middle cerebral artery | 10 (48%) | 83 (78%) | |
| Ischemic core imaging study | 71% CTP, 29% MRI-DWI | 63% CTP, 37% MRI-DWI | 0.46 |
| Ischemic core volume, mL | 7.3±11.2 | 11.1±11.2 | 0.15 |
| TLKW to groin puncture, hours (median (IQR)) | 48 (30–72) | 12.8 (106–16.7) | N/A |
| Device/technique. n (%) | |||
| Manual aspiration only | 5 (24%) | 0 (0%) | <0.0001 |
| Stentriever assisted | 16 (76%) | 107 (100%) | |
| Number of passes | 2.5±2 | 2.4±1.5 | 0.79 |
↵N/A, insufficient individual patient level data for DAWN trial to compare median (IQR) between the two groups.