Table 1

Terminology

TermDescription
Prehospital triage modelPatients with suspected ELVO are triaged in the prehospital setting and routed directly to an ECC, bypassing any NECCs that may be geographically closer. At the ECC, patients may be treated with alteplase and/or EVT
NECC triage modelWhen a NECC is the geographically closest hospital, patients with suspected ELVO are brought to the NECC for triage. Patients may be treated with alteplase at the NECC and/or subsequently transferred to an ECC for treatment with EVT
Door-to-needle (DTN) timeTime from arrival at the receiving hospital to administration of alteplase
Door-to-puncture (DTP) timeTime from arrival at the receiving hospital to the start of the EVT procedure
Door-in-door-out timeWhen transferring a patient from a NECC to an ECC for potential EVT, this describes the time from arrival at the NECC to transfer departure from the NECC
Onset-to-needleTime from the onset of stroke symptoms to administration of alteplase
Onset-to-punctureTime from the onset of stroke symptoms to the start of the EVT procedure
Needle-to-punctureIn those receiving both alteplase and EVT, this describes the time from administration of alteplase to the start of the EVT procedure
Onset-to-reperfusionTime from onset of stroke symptoms to reperfusion of the affected vasculature with EVT
  • ECC, endovascular-capable center; ELVO, emergent large vessel occlusion; EVT, endovascular thrombectomy; NECC, non-endovascular-capable center.