Reasons for not receiving off-label ET (n=105) | N (%)‡ |
Large infarct core >70 mL | 51 (49%) |
Baseline mRS >2 | 29 (28%) |
Completed infarct§ | 28 (27%) |
Patient did not consent or opted against ET | 4 (4%) |
*10% of patients had more than one reason for trial ineligibility.
↵†DAWN: age ≥80 years, NIHSS ≥10 and infarct volume ≤21 mL; age <80 years, NIHSS ≥10 and infarct volume ≤31 mL or NIHSS ≥20 and infarct volume ≤51 mL. DEFUSE-3: ischemic core volume <70 mL, mismatch ratio ≥1.8 and mismatch volume ≥15 mL.
‡8% of patients had more than one reason for not receiving ET.
§The term ‘completed Infarct’ used here implies that, while the ischemic core volume <70 mL, there was little to no salvageable penumbra on perfusion imaging.
ET, endovascular thrombectomy; mRS, modified Rankin Scale; NIHSS, NIH Stroke Scale.