Characteristics | Overall (n=281) | Number of passes | P values | |
≤3 (n=212) | >3 (n=69) | |||
Demographics | ||||
Age, years, mean (SD) | 69.4 (14.6) | 69.4 (15.0) | 69.2 (13.5) | 0.92 |
Men | 135/281 (48.0) | 95/212 (44.8) | 40/69 (58.0) | 0.057 |
Medical history | ||||
Hypertension | 168/276 (60.9) | 123/208 (59.1) | 45/68 (66.2) | 0.30 |
Diabetes | 56/277 (20.2) | 39/209 (18.7) | 17/68 (25.0) | 0.26 |
Hypercholesterolemia | 104/276 (37.7) | 80/209 (38.3) | 24/67 (35.8) | 0.72 |
Current smoking | 51/233 (21.9) | 39/174 (22.4) | 12/59 (20.3) | 0.74 |
Coronary artery disease | 50/275 (18.2) | 35/207 (16.9) | 15/68 (22.1) | 0.34 |
Previous stroke or TIA | 48/278 (17.3) | 37/210 (17.6) | 11/68 (16.2) | 0.78 |
Previous antithrombotic medication | 135/276 (48.9) | 102/207 (49.3) | 33/69 (47.8) | 0.83 |
Antiplatelet | 89/276 (32.2) | 65/207 (31.4) | 24/69 (34.8) | 0.60 |
Anticoagulant | 52/276 (18.8) | 40/207 (19.3) | 12/69 (17.4) | 0.72 |
Current stroke event | ||||
Systolic blood pressure, mmHg, mean (SD)* | 148 (25) | 147 (24) | 151 (26) | 0.26 |
NIHSS score, mean (SD)† | 16.1 (6.2) | 16.1 (6.4) | 16.0 (5.5) | 0.96 |
Pre-stroke mRS≥1 | 50/280 (17.9) | 40/211 (19.0) | 10/69 (14.5) | 0.40 |
ASPECTS, median (IQR)‡ | 7 (6 to 9) | 8 (6 to 9) | 6 (4 to 8) | <0.001 |
Site of occlusion | ||||
M1-MCA | 165/281 (58.7) | 126/212 (59.4) | 39/69 (56.5) | 0.90 |
M2-MCA | 67/281 (23.9) | 50/212 (23.6) | 17/69 (24.7) | |
Intracranial ICA | 49/281 (17.4) | 36/212 (17.0) | 13/69 (18.8) | |
Favorable collaterals | 61/227 (26.9) | 46/174 (26.4) | 15/53 (28.3) | 0.79 |
Cardioembolic stroke etiology | 125/281 (44.5) | 93/212 (43.9) | 32/69 (46.4) | 0.72 |
Intravenous rt-PA | 184/281 (65.5) | 142/212 (67.0) | 42/69 (60.9) | 0.35 |
Endovascular treatment | ||||
First-line CA strategy | 139/281 (49.5) | 96/212 (45.3) | 43/69 (62.3) | 0.014 |
General anesthesia | 30/281 (10.7) | 24/212 (11.3) | 6/69 (8.7) | 0.54 |
Onset to recanalization, min, median (IQR)§ | 280 (220 to 336) | 266 (215 to 320) | 315 (248 to 353) | <0.001 |
Onset to clot contact¶ | 250 (200 to 302) | 250 (202 to 306) | 260 (184 to 298) | 0.74 |
Clot contact to recanalization§ | 18 (7 to 38) | 12 (6 to 24) | 50 (39 to 75) | <0.001 |
Near or complete recanalization (mTICI 2 c/3) | 194/281 (69.0) | 160/212 (75.5) | 34/69 (49.3) | <0.001 |
Values expressed as no./total no. (%) unless otherwise indicated.
*six missing values.
†three missing values.
‡four missing values.
§one missing value.
¶two missing values.
ASPECTS, Alberta stroke program early CT score; CA, contact aspiration; ICA, internal carotid artery; IQR, IQR range; MCA, middle cerebral artery; MRI, MRI resonance imaging; NIHSS=National Institutes of Health Stroke Scale; rt-PA, recombinant tissue plasminogen activator; TIA, transient ischemic attack.