Table 1

Comparison of baseline characteristics, and procedural and outcome measures in patients aged 60–<80 years and those aged ≥80 years

VariablenTotalAge 60–<80 years (n=227)Age ≥80 years (n=108)Test usedTest summary (P value)
Preprocedure
 Age (years)33574.6 (8.9)69.7 (5.9)84.7 (4.2)t test<0.0001
 Women (n (%))335177 (53.2)103 (45.8)74 (68.5)χ2 <0.01
 White (n (%))335214 (64.3)145 (64.4)69 (63.9)χ2 >0.05
 Pre-stroke mRS 0–2 (n (%))319289 (90.6)196 (92.8)93 (86.1)χ2 >0.05
 Baseline NIHSS33516.3 (7.5)15.8 (7.9)17.3 (6.5)t test>0.05
 Time from onset to groin (min)319444.3 (684)459.5 (581)413.9 (856.7)t test>0.05
 IV tPA (n (%))333130 (39)81 (36)49 (45.3)χ2 >0.05
 No of vessels (median (IQR))3301 (1)1 (1)1 (1)MW>0.05
 Posterior circulation (n (%))33535 (10)28 (12)7 (7)χ2 >0.05
 ASPECT score3118 (1.9)7.8 (2.1)8.5 (1.4)t test<0.001
Comorbidities (n (%))
 Diabetes33399 (29.7)66 (29.1)32 (29.6)χ2 >0.05
 Hypertension333270 (81.1)162 (71.4)90 (83.3)χ2 >0.05
 Afib333128 (38.4)98 (44.0)55 (50.9)χ2 >0.05
 Hyperlipidemia333164 (49.2)107 (47.2)56 (51.9)χ2 >0.05
 Prior stroke33561 (20.6)41 (18.1)28 (25.9)χ2 >0.05
Procedure
 Time to recanalization (min)32229.7 (24.6)29.1 (23.5)30.9 (26.9)t test>0.05
 IA tPA (n (%))33349 (14.7)35 (15.6)13 (12)χ2 >0.05
 No of devices3332 (1)2 (1)2 (1)MW>0.05
 Device*331χ2 >0.05
  Stent retreivers109 (32.9)74 (32.9)35 (33)
  Stents10 (3)8 (3.6)2 (1.9)
  Balloons12 (3.6)9 (4)3 (2.8)
 No of passes3332 (3)2 (3)2 (4)MW>0.05
 No of passes (n (%))333χ2 >0.05
   1111 (33.3)71 (31.6)40 (37)
   276 (22.8)55 (24.4)21 (19.4)
   338 (11.4)30 (13.3)8 (7.4)
   >3106 (31.8)69 (30.7)37 (34.3)
 Final TICI flow (n (%))333χ2 >0.05
  2B–3309 (92.8)212 (94.2)97 (89.8)
  0–2A24 (7.2)13 (5.8)11 (10.2)
 Complications (n (%))33311 (3.3)8 (3.6)3 (2.8)χ2 >0.05
 Hemorrhage, all types (n (%))333127 (38.1)82 (36.4)45 (41.7)χ2 >0.05
  Hemorrhage, PH233320 (6.0)14 (6.2)6 (5.6)χ2 >0.05
Outcome (90 day)
 mRS (median (IQR))3323 (4)3 (4)4 (3)MW<0.0001
 mRS dichotomized (n (%))332χ2 <0.0001
  mRS 0–2125 (36.7)100 (44.4)22 (20.5)
  mRS >2207 (62.4)125 (55.6)85 (79.5)
 Death (n (%))33382 (24.6)45 (20)37 (34.3)χ2 <0.001
 Length of stay (days)3329.5 (10.9)9.1 (8.6)10.5 (14.6)t test>0.05
  • Values are n (%), mean (SD), or median (IQR).

  • χ2 test was used for categorical variables, the Student’s t test was used for parametric variables, and the Mann–Whitney test was used for non-parametric variables.

  • *Other devices include reperfusion catheters, Penumbra separators, embolic protectors, and others. 

  • Afib, atrial fibrillation; ASPECT score, Alberta Stroke Program Early CT score; IV tPA, intravenous tissue plasminogen activator; mRS, modified Rankin Scale; MW, Mann–Whitney test; NIHSS, National Institutes of Health Stroke Scale; PH2, parenchymal hematoma;  TICI, Thrombolysis in Cerebral Ischemia.