Comparison of patients at least 80 years old who had good versus poor outcome after thrombectomy
| Variable | Good outcome | Poor outcome | Univariate analysis | Included in regression | Multivariate (n=103) | ||
| n=22 | n=85 | Test | P value | OR | 95% CI | ||
| Preprocedure | |||||||
| Age (years) | 85 (4.2) | 84.7 (4.2) | t test | p>0.05 | Yes* | ||
| Women (n (%)) | 15 (68) | 58 (68) | χ2 | p>0.05 | Yes* | 0.76 | 0.19 to 3.1 |
| White (n (%)) | 15 (68) | 53 (62) | χ2 | p>0.05 | Yes* | 0.72 | 0.29 to 6.11 |
| Baseline NIHSS | 12.3 (6.8) | 19.1 (5.4) | t test | p<0.001 | Yes | 0.82 | 0.72 to 0.94 |
| Pre-stroke mRS | 0 (1) | 1 (2) | MW | p<0.001 | Yes | 0.54 | 0.25 to 1.15 |
| Time from onset to groin (min) | 697.9 (1031) | 345 (311.3) | t test | p<0.05 | Yes | 1.00 | 0.99 to 1.01 |
| IV tPA (n (%)) | 9 (41) | 41 (48) | χ2 | p>0.05 | Yes* | 0.56 | 0.29 to 5.9 |
| No of vessels (median (IQR)) | 1 (0) | 1 (1) | MW | p<0.05 | Yes | 0.56 | 0.15 to 2.1 |
| ASPECT score | 8.8 (1.3) | 8.4 (1.4) | t test | P>0.05 | No | ||
| Comorbidities (n (%)) | |||||||
| Diabetes | 6 (27) | 25 (29) | χ2 | p>0.05 | Yes* | 1.15 | 0.2 to 5.62 |
| Afib | 18 (82) | 71 (84) | χ2 | p>0.05 | Yes* | 1.12 | 0.2 to 5.1 |
| Hyperlipidemia | 11 (50) | 44 (52) | χ2 | p>0.05 | Yes* | 0.66 | 0.2 to 2.53 |
| Hypertension | 12 (55) | 43 (51) | χ2 | p>0.05 | Yes* | 1.62 | 0.2 to 14.2 |
| Prior stroke | 5 (23) | 23 (27) | χ2 | p>0.05 | Yes* | 1.20 | 0.2 to 5.82 |
| Procedure | |||||||
| Time to recanalization (min) | 22.5 (15.3) | 32.8 (28.9) | t test | p>0.05 | No | ||
| IA tPA (n (%)) | 3 (14) | 9 (11) | χ2 | p>0.05 | No | ||
| No of devices | 2 (1) | 2 (1) | MW | p>0.05 | No | ||
| Device† | 2 | p>0.05 | No | ||||
| Stent retreivers | 3 (14) | 32 (39) | χ2 | ||||
| Stents | 0 (0) | 2 (2) | χ2 | ||||
| Balloons | 0 (0) | 3 (4) | χ2 | ||||
| No of passes | 1 (3) | 3 (4) | MW | p<0.01 | Yes | 5.62 | 1.2 to 25.29 |
| Passes >3 (n (%)) | 3 (14) | 33 (39) | χ2 | p<0.05 | No | ||
| Final TICI flow (n (%)) | χ2 | p>0.05 | No | ||||
| 0−2A | 0 (0) | 10 (13) | χ2 | ||||
| 2B−3 | 22 (100) | 74 (87) | |||||
| Complications (n (%)) | 1 (5) | 2 (2) | χ2 | p>0.05 | No | ||
| Hemorrhage, all types (n (%)) | 4 (18) | 41 (48) | χ2 | p<0.001 | Yes | ||
| Hemorrhage, PH2 | 0 (0) | 6 (7.1) | χ2 | No | |||
| Length of stay (days) | 5.4 (4.4) | 11.9 (16.1) | t test | p<0.001 | No | ||
Values are n (%), mean (SD), or median (IQR).
χ2 test was used for categorical variables, Student’s t test was used for parametric variables, and Mann−Whitney test was used for non-parametric variables.
↵*Despite absence of significance on univariate analysis, variables were included in multivariate analysis for clinical significance.
†Other devices include reperfusion catheters, P enumbra separators, embolic protectors, and others.
Afib, atrial fibrillation; ASPECT score, Alberta Stroke Program Early CT score; IA tPA, intra-arterial tissue plasminogen activator; IV tPA, intravenous tissue plasminogen activator; mRS, modified Rankin Scale; MW, Mann–Whitney test; NIHSS, National Institutes of Health Stroke Scale; PH2, parenchymal hematoma; TICI, Thrombolysis in Cerebral Ischemia.