Variable | N | Non-FAR | FAR | P values | N | Non-FAR | First pass | P values |
TICI 2b+ | TICI 2b+ | TICI 2c+ | TICI 2c+ | |||||
(n=302) | (n=178) | (n=189) | (n=156) | |||||
Preprocedure | ||||||||
Age (years) | 480 | 67.4 (14.3) | 68.4 (14.6) | >0.05 | 345 | 66.3 (14.5) | 67.8 (14.5) | >0.05 |
Female (n (%)) | 480 | 147 (49) | 95 (53) | >0.05 | 345 | 90 (48) | 86 (55) | >0.05 |
White (n (%)) | 480 | 170 (56) | 98 (55) | >0.05 | 345 | 107 (57) | 91 (58) | >0.05 |
Baseline NIHSS score | 479 | 16.3 (7.5) | 15.2 (7.6) | >0.05 | 345 | 16.1 (7.6) | 15.4 (7.6) | >0.05 |
Pre-stroke mRS score (median (IQR)) | 478 | 0 (1) | 0 (1) | >0.05 | 345 | 0 (1) | 0 (1) | >0.05 |
Time from onset to groin (min) | 480 | 482.1 (605.1) | 503.2 (715.1) | >0.05 | 345 | 525.6 (718.8) | 456.5 (368) | >0.05 |
IV tPA (n (%)) | 478 | 116 (38) | 83 (47) | >0.05 | 345 | 76 (40) | 73 (47) | >0.05 |
Comorbidities (n (%)) | ||||||||
Diabetes | 480 | 88 (29) | 50 (28) | >0.05 | 345 | 53 (28) | 45 (29) | >0.05 |
Hypertension | 480 | 223 (74) | 134 (75) | >0.05 | 345 | 140 (74) | 117 (75) | >0.05 |
AF | 480 | 92 (30) | 53 (30) | >0.05 | 345 | 59 (31) | 46 (29) | >0.05 |
Hyperlipidemia | 480 | 134 (44) | 74 (42) | >0.05 | 345 | 87 (46) | 67 (43) | >0.05 |
Procedure | ||||||||
Time to recanalization (min) | 480 | 33.4 (24) | 16.5 (14.3) | <0.01 | 345 | 31.4 (23.8) | 15.1 (9.4) | <0.01 |
Complications (n (%)) | 452 | 11 (3) | 3 (2) | >0.05 | 345 | 2 (1) | 2 (1) | >0.05 |
Hemorrhage, all types (n (%)) | 480 | 120 (40) | 52 (29) | <0.01 | 345 | 63 (33) | 46 (29) | >0.05 |
Hemorrhage, PH2 | 468 | 18 (6) | 5 (3) | >0.05 | 345 | 10 (5) | 2 (1) | <0.05 |
Outcome (90 day) | ||||||||
mRS dichotomized (n (%)) | 480 | <0.05 | 345 | =0.08 | ||||
mRS 0–2 | 122 (40) | 95 (53) | 83 (44) | 83 (53) | ||||
mRS >2 | 180 (60) | 83 (47) | 106 (56) | 73 (47) | ||||
Death (n (%)) | 480 | 65 (22) | 21 (12) | <0.01 | 345 | 42 (22) | 19 (12) | <0.01 |
Values are n (%) or mean (SD) or median (IQR).
χ2 Test for categorical variables, Student’s t-test was used for parametric variables, or Mann-Whitney test was used for non-parametric variables.
†AF, atrial fibrillation; FAR, first-attempt recanalization; IV tPA, intravenous tissue plasminogen activator; mRS, modified Rankin Scale; MW, Mann-Whitney test; NIHSS, National Institutes of Health Stroke Scale; PH2, parenchymal hematoma 2; TICI, Thrombolysis in Cerebral Infarction.