Summary of findings for PICO 1
Certainty assessment | № of patients | Effect | Quality of evidence | Importance | ||||||||
№ of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | MT+BMM | BMM alone | Relative (95% CI) | Absolute (95% CI) | ||
3-Month mRS score 0–2 | ||||||||||||
9 | Randomized trials | Not serious | Not serious | Not serious | Not serious | None | 453/951 (47.6%) | 295/955 (30.9%) |
RR=1.50
(1.34 to 1.68) OR=2.03 (1.68 to 2.46) |
154 more per 1 000
(from 105 more to 210 more) | ⨁⨁⨁⨁ HIGH | CRITICAL |
BMM, best medical management; CI, confidence interval; RR, risk ratio; MT, mechanical thrombectomy.