Demographics, clinical characteristics, and treatment details of the TRACK Registry
| 0–6 Hours (N=559) | 6–16 Hours (N=248) | 16–24 Hours (N=20) | >24 Hours (N=3) | P values | |
| Demographics | |||||
| Age (years), mean±SD Median (IQR) | 67.4±14.9 70 (57–79) | 66.1±14.6 68 (55–78) | 69.9±14 73 (57–79) | 80.3±14.2 87 (64–90) | 0.2 |
| Female sex, n (%) | 277/559 (40.6%) | 121/248 (48.8%) | 15/19 (78.9%) | 2/3 (66.7%) | 0.14 |
| Age >80 years, n (%) | 122/559 (21.8%) | 46/248 (18.5%) | 4/20 (20%) | 2/3 (66.7%) | 0.18 |
| Race, white, n (%) | 391/557 (70.2%) | 174/245 (71.0%) | 15/19 (78.9%) | 3/3 (100%) | 0.14 |
| Hypertension, n (%) | 427/557 (76.7%) | 185/248 (74.6%) | 13/20 (65%) | 3/3 (100%) | 0.45 |
| Atrial fibrillation, n (%) | 246/557 (44.2%) | 96/248 (38.7%) | 10/20 (50%) | 1/3 (33.3%) | 0.45 |
| Diabetes mellitus, n (%) | 139/558 (24.9%) | 84/248 (33.9%) | 10/20 (50%) | 0 | 0.03 |
| Hyperlipidemia, n (%) | 287/558 (51.4%) | 120/248 (48.4%) | 5/20 (25%) | 3/3 (100%) | 0.22 |
| Any history of smoking, n (%) | 133/544 (24.4%) | 76/247 (30.8%) | 5/20 (25%) | 0 | 0.16 |
| Coronary artery disease, n (%) | 156/481 (32.4%) | 57/219 (26%) | 6/15 (40%) | 1/3 (33.3%) | 0.32 |
| Clinical data | |||||
| Admission systolic BP (mm Hg), mean±SD, median (IQR) | 144.3±26.3 144 (125–160) | 145±27 141 (127–163) | 145.7±32.5 143 (127–159.3) | 146±29.6 143 (118–177) | 0.98 |
| Admission diastolic BP (mm Hg), mean±SD, median (IQR) | 77.6±18.7 78 (66–87) | 79.2±18.9 78 (69–90) | 79.2±19.6 80.5 (62.5–94) | 81.7±9.3 79 (74–92) | 0.7 |
| Intravenous tPA use, n (%) | 341/557 (61.2%) | 78/248 (31.5%) | 0 | 0 | <0.0001 |
| Baseline NIHSS score, mean±SD Median (IQR) | 17.9±5.9) 18 (15–21) | 16.4±5.9 16 (13–20) | 16.4±5.7 16 (12–20) | 18±3 18 (14–22) | 0.007 |
| Occlusion site | |||||
| MCA M1/M2, n (%) | 295/556 (53.1%) | 144/247 (58.3%) | 12/20 (60%) | 1/3 (33.3%) | |
| MCA M3, n (%) | 128/556(23%) | 56/247 (22.7%) | 5/20 (25%) | 2/3 (66.7%) | |
| ACA, n (%) | 3/556 (0.5%) | 0 | 2/20 (10%) | 0 | |
| ICA (cervical/intracranial), n (%) | 130/556 (23.4%) | 47/247 (19%) | 1/20 (5%) | 0 | |
ACA, anterior cerebral artery; BP, blood pressure; ICA, internal carotid artery; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; tPA, tissue plasminogen activator.