Risk factor analysis for recanalization after coil embolization of posterior communicating artery (PcoA) aneurysms in hypoplastic variants
| Recanalization (%) | Univariate analysis | Multivariate analysis | |||
| Variable | No (n=184) | Yes (n=107) | P values | P values | OR (95% CI) |
| Sex | 0.901 | ||||
| Female | 152 (82.6) | 89 (83.2) | |||
| Male | 32 (17.4) | 18 (16.8) | |||
| Age (years) | 0.176 | ||||
| ≤65 | 133 (72.3) | 85 (79.4) | |||
| >65 | 51 (27.7) | 22 (20.6) | |||
| Hypertension | 100 (54.3) | 53 (49.5) | 0.428 | ||
| Diabetes mellitus | 25 (13.6) | 7 (6.5) | 0.070 | 0.183 | 0.519 (0.198 to 1.361) |
| Hyperlipidemia | 71 (38.6) | 30 (28.0) | 0.069 | 0.250 | 0.715 (0.403 to 1.267) |
| Smoking | 25 (13.6) | 8 (7.5) | 0.118 | ||
| Presentation | 0.046 | 0.357 | 1.338 (0.720 to 2.489) | ||
| UIA | 148 (80.4) | 75 (70.1) | |||
| SAH | 36 (19.6) | 32 (29.9) | |||
| PcoA/P1 ratio >0.5 | 126 (68.5) | 83 (77.6) | 0.098 | 0.411 | 1.286 (0.706 to 2.342) |
| PcoA angulation >90° | 30 (16.3) | 11 (10.3) | 0.158 | ||
| Maximum size (mm) | <0.01 | <0.01 | 3.401 (1.605 to 7.206) | ||
| ≤7 mm | 165 (89.7) | 73 (68.2) | |||
| >7 mm | 19 (10.3) | 34 (31.8) | |||
| Neck size (mm) | <0.01 | 0.122 | 1.670 (0.872 to 3.197) | ||
| ≤4 mm | 141 (76.6) | 63 (58.9) | |||
| >4 mm | 43 (23.4) | 44 (41.1) | |||
| Depth to neck ratio (>1.5) | 49 (26.6) | 34 (31.8) | 0.349 | ||
| Retreatment with recanalization | 19 (10.3) | 23 (21.5) | 0.010 | <0.01 | 3.234 (1.511 to 6.923) |
| Residual sac | 43 (23.4) | 31 (29.0) | 0.291 | ||
| Use of stent | 43 (23.4) | 20 (18.7) | 0.351 | ||
| PcoA flow compromise | 0.035 | <0.01 | |||
| Incomplete compromise | 35 (19.0) | 18 (16.8) | 0.385* | 0.170* | 0.607 (0.298 to 1.238) |
| Complete compromise | 24 (13.0) | 4 (3.7) | 0.012* | <0.01* | 0.160 (0.047 to 0.545) |
| Preservation | 125 (68.0) | 85 (79.5) | Reference | ||
*Reference variable; preservation of PcoA flow.
SAH, subarachnoid hemorrhage; UIA, unruptured intracranial aneurysm.