Baseline characteristics according to susceptibility vessel sign (SVS) on MRI
| Characteristics | SVS– (n=52) | SVS+ (n=165) | P values† |
| Demographics | |||
| Age, years, mean (SD) | 65.7 (14.1) | 64.5 (15.4) | 0.98 |
| Men | 21/52 (40.4) | 91/165 (55.2) | 0.095 |
| Medical history | |||
| Hypertension | 33/52 (63.5) | 79/161 (49.1) | 0.17 |
| Diabetes | 13/52 (26.5) | 17/163 (10.4) | 0.066 |
| Hypercholesterolemia | 19/49 (38.8) | 60/155 (38.7) | 0.89 |
| Current smoking | 8/45 (17.8) | 33/143 (23.1) | 0.49 |
| Coronary artery disease | 9/51 (17.6) | 21/161 (13.0) | 0.78 |
| Current stroke event | |||
| Systolic blood pressure, mmHg, mean (SD)‡ | 142.1 (26.1) | 142.1 (22.9) | 0.85 |
| Diastolic blood pressure, mmHg, mean (SD)‡ | 81.0 (17.4) | 81.0 (15.1) | 0.86 |
| Glycemia, median (IQR)§ | 6.6 (5.6 to 7.7) | 6.7 (5.9 to 8.2) | 0.071 |
| NIHSS score, mean (SD)¶ | 16.2 (6.0) | 16.7 (5.6) | 0.91 |
| ASPECTS, median (IQR)** | 7 (5 to 8) | 7 (5 to 8) | 0.66 |
| Site of occlusion | 0.082 | ||
| M1/M2 | 40/52 (76.9) | 144/165 (87.3) | |
| ICA | 12/52 (23.1) | 21/165 (12.7) | |
| Intravenous rt-PA | 35/52 (67.3) | 141/165 (85.5) | 0.15 |
| Etiology | 0.38 | ||
| Atherothrombotic | 8/51 (15.7) | 17/161 (10.6) | |
| Cardioembolic | 17/51 (33.3) | 72/161 (44.7) | |
| Other or unknown causes | 26/51 (51.0) | 72/161 (44.7) | |
| Favorable collaterality | 10/42 (23.8) | 26/139 (18.7) | 0.56 |
| Intervals times, min, median (IQR) | |||
| Onset to groin puncture time†† | 220 (165 to 296) | 215 (180 to 255) | 0.57 |
| Onset to imaging‡ | 102 (72 to 135) | 115 (88.5 to 141) | 0.089 |
| Onset to clot‡‡ | 252 (200 to 325) | 248 (210 to 285) | 0.57 |
Values expressed as the no/total no (%) unless otherwise indicated.
P values were computed using logistic regression model adjusted for study (except for Intravenous rt-PA).
†P values calculated after log- transformation of data.
‡Two missing values (one in SVS+).
§Seven missing values (four in SVS+).
¶One missing value in SVS–.
**Four missing values (three in SVS+).
††Three missing values (two in SVS+).
‡‡Five missing values (four in SVS+).
ASPECTS, Alberta Stroke Programme Early CT Score; ICA, internal carotid artery; IQR, IQR range; M1,M2, first or second segment of the middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; rt-PA, recombinant tissue plasminogen activator; SVS, susceptibility vessel sign.