Study population
| Characteristic | Mean±SD (N), median (IQR) or % (n/N) |
| Age (years) | 65.4±13.5 (729); 67.0 (56.8–76.0) |
| Female sex | 47.5% (346/729) |
| NIHSS at baseline | 17.1±4.8 (725); 17.0 (14.0–20.0) |
| ASPECTS at baseline | 7.6±1.8 (722); 8.0 (7.0–9.0) |
| Collateral grade | |
| 0 | 0.9% (5/562) |
| 1 | 13.7% (77/562) |
| 2 | 44.3% (249/562) |
| 3 | 41.1% (231/562) |
| tPA delivered | 85.7% (625/729) |
| Onset to randomization (min) | 205.7±96.9 (728); 184.5 (140.5–246.3) |
| Onset to arterial puncture (min) | 252.6±96.8 (685); 240.0 (185.0–300.0) |
| eTICI category post-procedure | |
| 0 | 8.2% (60/729) |
| 1 | 2.6% (19/729) |
| 2a (0–49%) | 13.7% (100/729) |
| 2b50 (50–66%) | 14.1% (103/729) |
| 2b67 (67–89%) | 29.9% (218/729) |
| 2c | 22.8% (166/729) |
| 3 | 8.6% (63/729) |
ASPECTS, Alberta Stroke Program Early CT Score; eTICI, expanded Thrombolysis In Cerebral Infarction; NIHSS, NIH Stroke Scale; tPA, tissue plasminogen activator.