Variable | N | Age | Age | Test used | Test summary |
<80 (n=1000) | ≥80 (n=346) | ||||
Preprocedure | |||||
Age (years) | 1346 | 62 (13) | 85 (5) | t Test | <0.001 |
Female (n (%)) | 1346 | 474 (47) | 230 (66) | χ2 | <0.01 |
White (n (%)) | 1346 | 666 (67) | 240 (69) | χ2 | >0.05 |
Pre-stroke mRS score (median (IQR)) | 1346 | 0 (1) | 0 (1) | MW | >0.05 |
Baseline NIHSS score | 1346 | 16 (7) | 17 (7) | t Test | <0.01 |
Time from onset to groin (hours) | 1346 | 399 (402) | 369 (527) | t Test | >0.05 |
IV tPA (n (%)) | 1346 | 445 (45) | 168 (49) | χ2 | >0.05 |
Number of comorbidities*(median (IQR)) | 1224 | 2 (1) | 2 (2) | MW | <0.05 |
Diabetes mellitus (n (%)) | 1224 | 243 (27) | 73 (23) | χ2 | >0.05 |
Hypertension (n (%)) | 1224 | 575 (63) | 229 (73) | χ2 | <0.05 |
Atrial fibrillation (n (%)) | 1224 | 241 (27) | 119 (38) | χ2 | <0.05 |
Hyperlipidemia (n (%)) | 1224 | 301 (33) | 120 (38) | χ2 | >0.05 |
Prior stroke | 1346 | 59 (6) | 28 (8) | χ2 | >0.05 |
Location | |||||
Anterior circulation (n (%)) | 1346 | 870 (87) | 310 (90) | χ2 | >0.05 |
Vessel involved (n (%)) | 1334 | χ2 | >0.05 | ||
ICA | 144 (15) | 50 (15) | |||
Tandem | 31 (3) | 13 (4) | |||
M1 | 495 (50) | 182 (53) | |||
M2 | 156 (16) | 55 (16) | |||
M3 | 25 (3) | 9 (3) | |||
Basilar | 106 (11) | 21 (6) | |||
Other† | 36 (4) | 11 (3) | |||
ASPECT score (median (IQR)) | 875 | 8 (2) | 9 (3) | MW | <0.01 |
Procedure | |||||
Time to recanalization (min) | 1022 | 48 (41) | 45 (33) | t Test | >0.05 |
IA tPA (n (%)) | 1298 | 155 (16) | 53 (16) | χ2 | >0.05 |
Aspiration at first pass (n (%)) | 1336 | 592 (59) | 188 (55) | χ2 | >0.05 |
Use of stent retrievers (n (%)) | 1336 | 531 (53) | 191 (56) | χ2 | >0.05 |
Use of additional devices‡ (n (%)) | 1336 | 131 (13) | 36 (10) | χ2 | >0.05 |
Number of passes (Mean (Median)) | 1299 | 2.5 (2) | 2.3 (2) | MW | <0.05 |
Number of passes (n (%)) | 1299 | χ2 | <0.05 | ||
<3 | 590 (61) | 227 (68) | |||
≥3 | 375 (39) | 107 (32) | |||
Final TICI score (n (%)) | 1346 | χ2 | >0.05 | ||
2b–3 | 884 (88) | 304 (88) | |||
0–2a | 116 (12) | 42 (12) | |||
TICI score 2C–3 (n (%)) | 1346 | 404 (40) | 130 (38) | χ2 | >0.05 |
Complications (n (%)) | 1346 | 50 (5) | 15 (4) | χ2 | >0.05 |
Hemorrhage, all types (n (%)) | 1101 | 251 (28) | 93 (42) | χ2 | <0.01 |
Hemorrhage, PH2 | 1101 | 33 (4) | 15 (7) | χ2 | 0.07 |
Outcome (90 day) | |||||
mRS (median (IQR)) | 1226 | 3 (4) | 4 (3) | MW | <0.001 |
mRS dichotomized (n (%)) | 1226 | χ2 | <0.001 | ||
mRS score 0–2 | 398 (44) | 65 (21) | |||
mRS score >2 | 515 (56) | 247 (79) | |||
Death (n (%)) | 1226 | 184 (20) | 118 (38) | χ2 | <0.001 |
NIHSS at discharge | 919 | 8.3 (10) | 13 (12) | t Test | <0.001 |
∆NIHSS (discharge-admission) | 919 | −7.5 (10) | −4 (12) | t Test | <0.01 |
Length of hospitalization (days) | 1094 | 11 (12) | 10 (11) | t Test | >0.05 |
Values are n (%) or mean (SD) or median (IQR).
χ2Test for categorical variables, Student’s t test was used for parametric variables, or the Mann-Whitney test for non-parametric variables.
*Number of comorbidities includes the number of comorbidities (hypertension, hyperlipidemia, diabetes, atrial fibrillation) present in each patient and ranges from 0 to 4.
†Other vessels include posterior cerebral artery, anterior cerebral artery, and vertebral arteries.
‡Other devices include reperfusion catheters, Penumbra separators, embolic protectors, and others.
ICA, internal carotid artery; mRS, modified Rankin Scale; MW, Mann-Whitney test; NIHSS, National Institutes of Health Stroke Scale; PH2, parenchymal hematoma 2; TICI, Thrombolysis in Cerebral Infarction; tPA, tissue plasminogen activator.