Comparison of baseline characteristics and outcome between FAR and non-FAR group based on recanalization status
| Variable | N | Non-FAR | FAR | P values | N | Non-FAR | First pass | P values |
| TICI 2b+ | TICI 2b+ | TICI 2c+ | TICI 2c+ | |||||
| (n=302) | (n=178) | (n=189) | (n=156) | |||||
| Preprocedure | ||||||||
| Age (years) | 480 | 67.4 (14.3) | 68.4 (14.6) | >0.05 | 345 | 66.3 (14.5) | 67.8 (14.5) | >0.05 |
| Female (n (%)) | 480 | 147 (49) | 95 (53) | >0.05 | 345 | 90 (48) | 86 (55) | >0.05 |
| White (n (%)) | 480 | 170 (56) | 98 (55) | >0.05 | 345 | 107 (57) | 91 (58) | >0.05 |
| Baseline NIHSS score | 479 | 16.3 (7.5) | 15.2 (7.6) | >0.05 | 345 | 16.1 (7.6) | 15.4 (7.6) | >0.05 |
| Pre-stroke mRS score (median (IQR)) | 478 | 0 (1) | 0 (1) | >0.05 | 345 | 0 (1) | 0 (1) | >0.05 |
| Time from onset to groin (min) | 480 | 482.1 (605.1) | 503.2 (715.1) | >0.05 | 345 | 525.6 (718.8) | 456.5 (368) | >0.05 |
| IV tPA (n (%)) | 478 | 116 (38) | 83 (47) | >0.05 | 345 | 76 (40) | 73 (47) | >0.05 |
| Comorbidities (n (%)) | ||||||||
| Diabetes | 480 | 88 (29) | 50 (28) | >0.05 | 345 | 53 (28) | 45 (29) | >0.05 |
| Hypertension | 480 | 223 (74) | 134 (75) | >0.05 | 345 | 140 (74) | 117 (75) | >0.05 |
| AF | 480 | 92 (30) | 53 (30) | >0.05 | 345 | 59 (31) | 46 (29) | >0.05 |
| Hyperlipidemia | 480 | 134 (44) | 74 (42) | >0.05 | 345 | 87 (46) | 67 (43) | >0.05 |
| Procedure | ||||||||
| Time to recanalization (min) | 480 | 33.4 (24) | 16.5 (14.3) | <0.01 | 345 | 31.4 (23.8) | 15.1 (9.4) | <0.01 |
| Complications (n (%)) | 452 | 11 (3) | 3 (2) | >0.05 | 345 | 2 (1) | 2 (1) | >0.05 |
| Hemorrhage, all types (n (%)) | 480 | 120 (40) | 52 (29) | <0.01 | 345 | 63 (33) | 46 (29) | >0.05 |
| Hemorrhage, PH2 | 468 | 18 (6) | 5 (3) | >0.05 | 345 | 10 (5) | 2 (1) | <0.05 |
| Outcome (90 day) | ||||||||
| mRS dichotomized (n (%)) | 480 | <0.05 | 345 | =0.08 | ||||
| mRS 0–2 | 122 (40) | 95 (53) | 83 (44) | 83 (53) | ||||
| mRS >2 | 180 (60) | 83 (47) | 106 (56) | 73 (47) | ||||
| Death (n (%)) | 480 | 65 (22) | 21 (12) | <0.01 | 345 | 42 (22) | 19 (12) | <0.01 |
Values are n (%) or mean (SD) or median (IQR).
χ2 Test for categorical variables, Student’s t-test was used for parametric variables, or Mann-Whitney test was used for non-parametric variables.
†AF, atrial fibrillation; FAR, first-attempt recanalization; IV tPA, intravenous tissue plasminogen activator; mRS, modified Rankin Scale; MW, Mann-Whitney test; NIHSS, National Institutes of Health Stroke Scale; PH2, parenchymal hematoma 2; TICI, Thrombolysis in Cerebral Infarction.