Univariable and multivariable associations of baseline characteristics with infarct in new territory (INT) on logistic regression models
| Univariable analyses | Univariable analyses | Multivariable analyses | ||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age | 1.01 (0.99 to 1.03) | 0.213 | – | – |
| African-American race | 1.48 (0.81 to 2.72) | 0.199 | – | – |
| Male sex | 0.64 (0.36 to 1.15) | 0.136 | – | – |
| Hypertension | 2.08 (0.90 to 4.77) | 0.085 | 1.57 (0.56 to 4.37) | 0.392 |
| Diabetes mellitus | 0.89 (0.47 to 1.67) | 0.719 | – | – |
| Hypercholesterolemia | 1.30 (0.73 to 2.31) | 0.369 | – | – |
| Congestive heart failure | 1.30 (0.73 to 2.32) | 0.372 | – | – |
| Current smoking | 0.66 (0.33 to 1.31) | 0.241 | – | – |
| History of stroke | 1.43 (0.72 to 2.82) | 0.306 | – | – |
| History of CAD | 1.56 (0.84 to 2.88) | 0.158 | – | – |
| Atrial fibrillation | 0.78 (0.38 to 1.58) | 0.488 | – | – |
| IV tPA | 0.48 (0.26 to 0.85) | 0.012 | 0.75 (0.32 to 1.76) | 0.506 |
| Good collaterals | 0.56 (0.30 to 1.06) | 0.075 | 0.68 (0.30 to 1.53) | 0.356 |
| Pretreatment with antiplatelets | 1.69 (0.94 to 3.05) | 0.079 | 1.26 (0.57 to 2.78) | 0.560 |
| Pretreatment with oral anticoagulant | 1.52 (0.72 to 3.23) | 0.275 | – | – |
| Pretreatment with statin | 0.81 (0.44 to 1.52) | 0.518 | – | – |
| Baseline NIHSS score | 1.01 (0.97 to 1.05) | 0.585 | – | – |
| Admission SBP | 1.01 (1.00 to 1.01) | 0.159 | – | – |
| Admission DBP | 1.00 (0.99 to 1.01) | 0.764 | – | – |
| Baseline ASPECTS score | 0.90 (0.73 to 1.10) | 0.298 | – | – |
| OTGPT | 1.01 (1.00 to 1.03) | 0.039 | 1.00 (0.99 to 1.01) | 0.211 |
| Admission serum glucose | 1.00 (0.99 to 1.01) | 0.188 | – | – |
| Occlusion site in posterior circulation | 0.28 (0.14 to 0.55) | <0.001 | 3.33 (1.43 to 7.69) | 0.005 |
| Proximal occlusion in anterior circulation | 0.64 (0.26 to 1.60) | 0.346 | – | – |
| Number of passes during MT | 1.22 (0.89 to 1.68) | 0.204 | – | – |
| Cardio-embolic cause of stroke | 0.82 (0.45 to 1.50) | 0.526 | ||
| General anesthesia | 1.07 (0.55 to 2.06) | 0.831 | ||
| Balloon guide use during MT | 1.14 (0.42 to 3.09) | 0.792 | ||
*Proximal, M1 and/or ICA (extra- or intracranial).
ASPECTS, Alberta Stroke Program Early CT Score; CAD, coronary artery disease; DBP, diastolic blood pressure; IV tPA, intravenous tissue plasminogen activator; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; OTGPT, onset-to-groin puncture time; SBP, systolic blood pressure.