Characteristics of the RACE alert (RACE ≥5) versus stroke alert (RACE <5) mechanical thrombectomy cohorts
| Characteristics | SA-MT (n=38) | RA-MT (n=125) | P value |
| Demographics | |||
| Age (median, IQR) | 77 (61.5–82) | 73 (65–84) | 0.83 |
| Gender (male, %) | 14 (36.8) | 53 (42.4) | 0.58 |
| Vascular risk factors (n, %) | |||
| Hypertension | 33 (86.8) | 102 (81.6) | 0.62 |
| Diabetes mellitus | 12 (31.6) | 33 (26.4) | 0.54 |
| Hyperlipidemia | 27 (71.1) | 87 (69.6) | 1.0 |
| Atrial fibrillation | 17 (44.7) | 58 (46.4) | 1.0 |
| Clinical presentation | |||
| Baseline NIHSS score (median, IQR) | 9 (5–18) | 16 (13–21) | <0.0001 |
| ASPECTS (median, IQR) | 9 (8–9) | 9 (8–9) | 0.67 |
| Occlusion site (n, %) | |||
| ICA terminus | 4 (10.5) | 28 (22.4) | 0.16 |
| M1 | 21 (55.3) | 57 (45.6) | 0.36 |
| M2 | 10 (26.3) | 27 (21.6) | 0.52 |
| M3 | 1 (2.6) | 5 (4) | 1.0 |
| Basilar | 4 (10.5) | 3 (2.4) | 0.054 |
| Tandem | 2 (5.3) | 13 (10.4) | 0.52 |
| IV tPA (n, %) | 13 (34.2) | 63 (50.4) | 0.10 |
| Angiographic outcomes (n, %) | |||
| Successful revascularization (mTICI ≥2b) | 30 (78.9) | 105 (84.0) | 0.47 |
| Clinical outcomes (n, %) | |||
| mRS score ≤2 | 24 (63.2) | 58 (46.4) | 0.10 |
| Mortality | 6 (15.8) | 31 (24.8) | 0.37 |
| Time metrics (min) (median, IQR) | |||
| Onset-to-ECC arrival | 167 (64–540) | 74 (45–327) | 0.03 |
| Dispatch-to-ECC arrival | 46 (33–134) | 31 (26–39) | 0.0002 |
| Dispatch-to-groin puncture | 155 (113–188) | 101 (82–118) | <0.0001 |
| Dispatch-to-recanalization | 173 (124–216) | 131 (113–160) | 0.02 |
| Door-to-groin puncture | 72 (52–114) | 67 (53–82) | 0.21 |
| Onset-to-groin puncture | 255 (129–564) | 157 (108–392) | 0.03 |
| Onset-to-recanalization | 282 (165–460) | 190 (134–398) | 0.054 |
ASPECTS, Alberta Stroke Program Early CT Score; ECC, endovascular capable center; ICA, internal carotid artery; mRS, modified Rankin Scale; MT, mechanical thrombectomy; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institutes of Health Stroke Scale; RA, RACE alert; SA, stroke alert; tPA, tissue plasminogen activator.