| Author and publication year | Group and No | IV tPA (n (%)) | Success recanalization (n (%)) | Complete recanalization (n (%)) | Procedure duration (min) | Favorable outcome (mRS 0–2) at 90 days (n (%)) | New territory embolic event (n (%)) | Any hemorrhagic complication (n (%)) | Hemorrhagic infarction (n (%)) | Parenchymatous hematoma (n (%)) | Subarachnoid hemorrhage (n (%)) | Mortality at 90 days (n (%)) | Conclusion |
| Kang19 2018 |
ADAPT (67) | NA | 63/67 (94) | 41/67 (61.2) | 40 (25–70) | 27/67 (40.3) | 6/212 (2.9) | 11/67 (16.5) | 9/67 (13.4) | 2/67 (2.9) | 0/67 (0) | 23/145 (15.9) | Endovascular thrombectomy was effective and safe for treating patients with acute BAO. This study showed no superiority of the SR over aspiration thrombectomy for treating acute BAO |
|
SR (145) | 131/145 (90.3) | 93/145 (64.1) | 68/145 (46.9) | 44/145 (30.3) | 30/145 (20.7) | 7/145 (4.8) | 7/145 (4.8) | 11/67 (16.5) | |||||
| Gory20 2018 |
ADAPT (46) | 23/46 (50) | 40/46 (87) | 25/46* (54.3) | 45* (34–62) | 18/45 (40) | 1/46* (2.2) | 5/39 (12.8) | NA | 2/39 (5.1) | 0/39 (0) | 21/45 (46.7) | This study indicates that in BAO patients, successful reperfusion is a strong predictor of a 90 day favorable outcome and that ADAPT as the firstline strategy improves the rate of complete reperfusion and reduces procedure duration |
|
SR (54) | 22/54 (40.7) | 39/54 (72.2) | 17/54* (31.5) | 56* (40–90) | 17/50 (34) | 10/54* (18.5) | 9/50 (18) | NA | 2/50 (4.0) | 1/50 (2.0) | 21/50 (42) | ||
| Gerber21 2017 |
ADAPT (20) | NA | 17/20 (85) AOL scale | 15/20 (75) AOL scale | 55±12* | 9/20 (45) mRS 0–3 at discharge | 2/20 (10) | 10/20 (50) | 7/20 (35) | 1/20 (5.0) | 2/20 (10) | 4/20 (20) discharge | In primarily embolic BAO, aspiration thrombectomy was faster, effective, and not detrimental to outcome compared with SR thrombectomy. Thus it may be justified to use aspiration thrombectomy as firstline treatment in these patients |
|
SR (13) | NA | 9/13 (69) AOL scale | 6/13 (46) AOL scale | 97±28* | 1/13 (7.7) mRS 0–3 at discharge | 3/13 (23.1) | 4/13 (30.8) | 2/13 (15.4) | 1/13 (7.7) | 1/13 (7.7) | 4/13 (30.8) discharge | ||
| Mokin22 2016 |
ADAPT (42) | 32/100 (32) | 35/42 (83.3) | NA | 46±28 | 14/42 (33.3) | NA | NA | NA | NA | NA | 30/100 (30) hospitalization | Time to the start of the procedure is an important predictor of clinical success after thrombectomy in patients with posterior circulation strokes. Both SR and aspiration thrombectomy as primary treatment approaches are effective in achieving successful recanalization |
|
SR (58) | 45/58 (57.7) | 56±44 | 21/58 (36.2) | ||||||||||
| Son23 2014 |
ADAPT (18) | 9/18 (50) | 18/18 (100) | 13/18* (72.2) | 62.3±34.8* | 8/18 (44.4) | 0/31 (0) | NA | NA | NA | NA | 7/18 (38.9) | The 2 thrombectomy devices were associated with similar recanalization rates and clinical outcomes in patients with AIS caused by BAO. However, Penumbra suction thrombectomy seemed to allow more rapid and complete recanalization than Solitaire thrombectomy |
|
SR (13) | 5/13 (38.5) | 11/13 (84.6) | 3/13* (23.1) | 101.9±41.4* | 5/13 (38.5) | 6/13 (46.2) |
Data are mean (SD), median (IQR), or n (%).
*Significant difference between two groups (P<0.05).
Gerber21used the AOL scale to assess reperfusion. AOL 2–3 and AOL 3 were defined as successful and complete recanalization, respectively. In their study, a favorable outcome was defined as an mRS score of 0–3, assessed at discharge, and mortality was during hospitalization (not at 90 days).
Mokin22reported mortality during hospitalization (not at 90 days).
Son23 reported both presentation time (defined as time from symptom onset to hospital presentation) and time to treatment (defined as presentation at the emergency room to entering the angiosuite). Both were listed in the column of ‘the time from onset to groin puncture’ with presentation time (up) and time to treatment (down).
AIS, acute ischemic stroke; AOL, arterial occlusive lesion; ASPECTS, Alberta Stroke Program Early CT Score; BA, basilar artery; CE, cardiogenic embolism; IV tPA, intravenous tissue plasminogen activator; LAA, large artery atherosclerosis; mRS, modified Rankin Scale; NA, not available; NIHSS, National Institutes of Health Stroke Scale; PCA, posterior cerebral artery; SR, stent retriever; VA, vertebral artery.