Significant predictors of a good 3-month clinical outcome in multivariate logistic regression model adjusted for age, admission NIHSS, arterial hypertension, diabetes mellitus, atrial fibrillation, pretreatment IVT, admission glycemia, recanalization time (onset to maximal achieved recanalization time), SICH, medians of SBP and DBP, and medians of maximal SBP and DBP. Subgroup analysis of all patients, patients with achieved recanalization (TICI 2b–3), and complete recanalization (TICI 3)
Subgroup | All patients | TICI 2b–3 patients | TICI 3 patients | ||||||
Variable | P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI |
Age | <0.0001 | 0.959 | 0.942 to 0.976 | 0.001 | 0.970 | 0.952 to 0.988 | 0.002 | 0.967 | 0.947 to 0.987 |
Admission NIHSS | <0.0001 | 0.898 | 0.870 to 0.927 | <0.0001 | 0.900 | 0.871 to 0.931 | <0.0001 | 0.891 | 0.859 to 0.925 |
Admission glycemia | 0.0001 | 0.839 | 0.767 to 0.918 | 0.001 | 0.861 | 0.785 to 0.944 | 0.0004 | 0.828 | 0.745 to 0.919 |
IV thrombolysis | 0.003 | 1.985 | 1.255 to 3.140 | 0.015 | 1.811 | 1.122 to 2.923 | 0.005 | 2.137 | 1.250 to 3.653 |
Recanalization time | <0.0001 | 0.995 | 0.993 to 0.997 | 0.0001 | 0.995 | 0.992 to 0.997 | 0.0001 | 0.994 | 0.991 to 0.997 |
SICH | 0.0005 | 0.055 | 0.007 to 0.425 | 0.010 | 0.066 | 0.008 to 0.522 | 0.004 | 0.049 | 0.006 to 0.385 |
Median max. SBP | NS | 0.038 | 0.990 | 0.981 to 0.999 | NS | ||||
Median DBP | 0.024 | 0.977 | 0.957 to 0.997 | NS | NS | ||||
Median max. DBP | NS | NS | 0.046 | 0.984 | 0.969 to 1.000 |
DBP, diastolic blood pressure; IV, intravenous; MT, mechanical thrombectomy, max., maximal; NIHSS, National Institutes of Health Stroke Scale; NS, not significant; SBP, systolic blood pressure; SICH, symptomatic intracerebral hemorrhage; TICI, Thrombolysis in Cerebral Infarction Scale.