Meta-regression of cumulative incidence of internal carotid artery restenosis
| Study level covariates | Restenosis >50% at 12 months | Restenosis >70% at 12 months | Restenosis >50% at 6 months | ||||||
| n | P value | R2 | n | P value | R2 | n | P value | R2 | |
| Methodology covariates | |||||||||
| Design of the study | |||||||||
| Multicenter | 3 | 0.78 | 0 | 2 | 0.06 | 34.7 | 0 | ||
| Single-center | 19 | 0 | 8 | 12 | |||||
| Publication year (years) | 22 | 0.51 | 0 | 10 | 0.90 | 0 | 12 | 0.58 | 0 |
| Study duration (years) | 21 | 0.89 | 0 | 10 | 0.54 | 0 | 11 | 0.32 | 0 |
| Cohort representativity | |||||||||
| Yes | 20 | 0.08 | 13.6 | 10 | 12 | ||||
| No | 2 | 0 | 0 | ||||||
| Population covariates | |||||||||
| Mean age (years) | 20 | 0.38 | 0 | 9 | 0.01 | 80.9 | 10 | 0.41 | 0 |
| Percentage of men (%) | 21 | 0.17 | 7.8 | 10 | 0.76 | 0 | 11 | 0.39 | 0 |
| Percentage with arterial hypertension (%) | 17 | 0.62 | 0 | 8 | 0.15 | 13.2 | 10 | 0.86 | 0 |
| Percentage of diabetes (%) | 16 | 0.42 | 0 | 8 | 0.30 | 0 | 9 | 0.10 | 33.2 |
| Percentage of smoking (%) | 16 | 0.13 | 9.9 | 8 | 0.35 | 0 | 7 | 0.74 | 0 |
| Percentage of symptomatic stenosis at baseline (%) | 17 | 0.6 | 0 | 7 | 0.05 | 54.2 | 9 | 0.61 | 0 |
| Presence of hostile neck in the study population | |||||||||
| Yes | 19 | 0.12 | 7.2 | 7 | 0.31 | 0 | 8 | 0.03 | 53.9 |
| No | 3 | 3 | 4 | ||||||
| Stent design | |||||||||
| Closed-cell | 7 | 0.59 | 0 | 3 | 0.99 | 0 | 7 | 0.86 | 0 |
| Open- and closed-cell | 11 | 4 | 4 | ||||||