Baseline demographics, clinical characteristics, and angiographic and clinical outcomes among patients with endovascular treatment with partial or complete recanalization
| Characteristics | Poor outcomes at 90 days (mRS score 3–6) | Good outcomes at 90 days (mRS score 0–2) | P value* |
| N | 40.5% (122) | 59.5% (179) | |
| Female, % (n/N) | 57% (69/122) | 58% (104/179) | 0.836 |
| Age, mean±SD (N) | 70±11 (122) | 65±13 (179) | <0.001 |
| Onset to groin puncture, mean±SD (N) | 283±92 (120) | 228±81 (173) | <0.001 |
| Groin puncture to recanalization, mean±SD (N) | 51±33 (118) | 44±25 (166) | 0.040 |
| Onset-to-recanalization, mean±SD (N) | 336±96 (117) | 273±86 (165) | <0.001 |
| Baseline NIHSS score, mean±SD (N) | 18.2±4.4 (119) | 15.9±4.6 (176) | <0.001 |
| Site of occlusion, % (n/N) | 0.256 | ||
| ICA | 24% (29/120) | 15% (27/179) | |
| M1 | 64% (77/120) | 72% (128/179) | |
| M2 | 11% (13/120) | 11% (19/179) | |
| M3 | 0% (0/120) | 1% (2/179) | |
| Other | 1% (1/120) | 1% (1/179) | |
| Posterior circulation | 0% (0/120) | 1% (2/179) | |
| Received Intravenous thrombolysis (IV tPA), % (n/N) | 65% (73/112) | 74% (125/168) | 0.109 |
| Hypertension, % (n/N) | 62% (76/122) | 65% (117/179) | 0.625 |
| Atrial fibrillation, % (n/N) | 41% (50/122) | 39% (69/179) | 0.719 |
| Hyperlipidemia, % (n/N) | 28% (34/122) | 35% (62/179) | 0.257 |
| Diabetes mellitus, % (n/N) | 23% (28/122) | 15% (26/179) | 0.068 |
| Myocardial disease, % (n/N) | 16% (20/122) | 16% (28/179) | 0.874 |
| Collaterals, mean±SD (N) | 1.9±0.9 (85) | 2.3±0.9 (132) | 0.005 |
| Baseline ASPECTS, mean±SD (N) | 8.0±1.8 (120) | 8.6±1.5 (179) | 0.004 |
| Glucose, mean±SD (N) | 138.8±61.8 (119) | 122.4±50.1 (172) | 0.013 |
| General anesthesia, % (n/N) | 65% (79/122) | 58% (103/179) | 0.231 |
| Number of device passes, % (n/N) | 0.559 | ||
| 1 | 55% (62/113) | 61% (99/162) | |
| 2 | 27% (30/113) | 24% (39/162) | |
| 3+ | 19% (21/113) | 15% (24/162) | |
| Final TICI grade, % (n/N) | 0.043 | ||
| 2b | 39% (47/122) | 27% (48/179) | |
| 3 | 61% (75/122) | 73% (131/179) | |
| Clinical outcomes | |||
| 90-Day NIHSS score, mean±SD (N) | 6.5±4.6 (75) | 1.1±1.5 (169) | <0.001 |
| ICH symptomatic (%) | 4% (5/122) | 1% (2/179) | 0.124 |
| ICH asymptomatic (%) | 17% (16/96) | 7% (9/132) | 0.030 |
*P value calculated from paired t-test for continuous measures and Fisher’s exact test for discrete measures.
ASPECTS, Alberta Stroke Program Early CT Score; ICA, internal carotid artery; ICH, intracranial hemorrhage; NIHSS, National Institutes of Health Stroke Scale; TIVI, Thrombolysis in Cerebral Infarction; tPA, tissue plasminogen activator.