HR-VWI of intracranial aneurysms with 1.5T and 3T scans
Author (year) | Sample size | Imaging technique | VWI enhancement analysis | Findings |
Hasan (2012)42 | 25 UIA (13 clipped, 12 observed) | 3T MRI T1, T2 and TOF MRA pre- and post- (24 and 72 hours) | Ferumoxytol-enhanced VWI |
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Matouk (2013)34 | 5 patients with SAH | 3T MRI pre- and post-gad | Subjective |
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Edjlali (2014)28 | 108 UIA (77 stable, 31 unstable)* | 3T MRI T1 pre- and T1 post-gad | CAWE analysis with multiplanar reconstructions |
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Coutinho (2015)35 | 11 patients (DSA-negative SAH) | 3T MRI T1 pre-, T2 pre-, and T1 post-gad | Subjective |
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Liu (2016)24 | 61 UIA | 3T MRI 3D TOF MRA pre-, black-blood T1W-VISTA pre- and post-gad | Subjective |
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Hu (2016)13 | 30 aneurysms (24 UIA, 6 ruptured) | 3T MRI TOF MRA pre-, DWI pre-, 3D T1 pre- and post-gad | Subjective |
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Nagahata (2016)30 | 144 aneurysms (61 ruptured, 83 UIA) | 3T MRI T1 pre- and post-gad | Subjective |
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Larsen (2018)14 | 13 UIA | 3T MRI T1 pre-, TOF MRA pre-, T1 post-, and TOF MRA post-gad | Subjective |
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Lv (2018)20 | 140 UIA | 3T MRI TOF MRA pre-, T1 pre- and post-gad | Subjective |
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Hudson (2018)16 | 10 UIA | 3T MRI T1 pre- and post-gad | Subjective |
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Omodaka (2018)29 | 162 aneurysms (95 UIA: 69 stable, 26 unstable; 67 ruptured)* | 3T or 1.5T MRI T1 pre-and post-, TOF MRA pre- and post-gad | Contrast ratio between CAWE and pituitary stalk (CRstalk) |
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Shimonaga (2018)15 | 9 UIA | 1.5T MRI TOF MRA pre-, T1 pre-, and T1 post-gad | Subjective |
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Backes (2018)23 | 89 UIA | 3T MRI 3D TOF MRA, 3D multishot TSE pre- and post-gad | Subjective |
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Edjlali (2018)31 | 333 aneurysms, (307 UIA: 276 stable, 31 unstable; 26 ruptured)* | 3T MRI T1 pre-, T1 post-gad | 4-grade enhancement: 0=none, 1=focal, 2=thin CAWE, 3=thick (>1 mm) CAWE |
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Zhang (2018)50 | 83 dissecting vertebrobasilar aneurysms | 3T MRI 3D TOF MRA pre-, T1 pre-, T2 pre- and T1 post-gad | Subjective |
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Hartman (2019)21 | 65 UIA (27 stable, 38 unstable)† | 3T MRI T1 pre- and post-, TOF MRA post-gad | Signal intensity analysis per quadrants and qualitative wall thinning |
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Wang (2019)25 | 88 UIA | 3T MRI 3D TOF MRA pre-, black-blood T1W-VISTA pre- and post-gad | Subjective |
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Wang (2019)32 | 89 UIA: 31 symptomatic, 58 asymptomatic | 3T MRI 3D TOF MRA pre-, T1 pre- and post-gad | Signal intensity measured in aneurysm neck, body and dome. ER calculated as (SImax − SIpre)/SIpre×100% |
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Quan (2019)18 | 54 UIA (9 histology specimens) | 3T MRI fat-suppressed 3D T1 pre- and T1 post-gad | Subjective |
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Gray rows highlight studies with histological correlate.
*Stable aneurysm defined as incidental/asymptomatic and non-evolving on serial 6-month follow-up.
†Stable aneurysm defined as PHASES score ≤3.
CAWE, circumferential aneurysm wall enhancement; CTA, CT angiography; DSA, digital substraction angiography; DWI, diffusion-weighted imaging; ER, enhancement ratio; MCA, middle cerebral artery; MRA, magnetic resonance angiography; MRI, magnetic resonance imaging; NPV, negative predictive value; PCOM, posterior communicating artery; SAH, subarachnoid hemorrhage; SI, signal intensity; TOF, time-of-flight; TSE, turbo spin-echo; UIA, unruptured intracranial aneurysm; VISTA, volume isotropic turbo-spin-echo acquisition; VWI, vessel wall imaging.