Table 1

Baseline characteristics comparing patients with basilar artery occlusion and patients with large vessel occlusion in the anterior circulation

CharacteristicsBAO (n=165)ACLVO (intracranial carotid artery, carotid-T, M1) (n=1574)P value
Clinical items
 Age (years)70 (59–80), N=16573 (61–82), N=15740.019
 Transfer from another hospital80/165 (48.5%)561/1572 (35.7%)0.002
 Sex (female)69/165 (41.8%)810/1574 (51.5%)0.022
 NIHSS on admission18 (8–30), N=15517 (12–20), N=15580.046
 Prestroke independence149/164 (90.9%)1446/1556 (92.9%)0.341
 Blood pressure systolic (mm Hg)148 (SD 31), N=86150 (SD 28), N=11410.413
 Blood pressure diastolic (mm Hg)78 (SD 16), N=8682 (SD 20), N=11390.097
 Admission glucose (mmol/L)7.5 (6.4–9.7), N=936.6 (5.8–8.1), N=1181<0.001
 Wake-up stroke13/161 (8.1%)123/1451 (8.5%)1.000
 TOAST etiology0.008
  Large artery37/163 (22.7%)205/1546 (13.3%)
  Cardioembolic64/163 (39.3%)733/1546 (47.4%)
  Other specific etiology12/163 (7.4%)101/1546 (6.5%)
  Unknown etiology50/163 (30.7%)507/1546 (32.8%)
Medication0.058
 Antiplatelet
  Monotherapy36/154 (23.4%)430/1463 (29.4%)
  Dual therapy0 (0%)26/1463 (1.8%)
 Statin32/142 (22.5%)395/1300 (30.4%)0.053
 Anticoagulation0.014
VKA10/154 (6.5%)180/1464 (12.3%)
  NOAC2/154 (1.3%)64/1464 (4.4%)
Risk factors
 Diabetes23/163 (14.1%)271/1555 (17.4%)0.326
 Arterial hypertension87/163 (53.4%)1046/1553 (67.4%)<0.001
 Dyslipidemia60/161 (37.3%)788/1547 (50.9%)0.001
 Smoking47/153 (30.7%)428/1499 (28.6%)0.574
 Previous stroke17/159 (10.7%)209/1565 (13.4%)0.389
 Coronary artery disease17/83 (20.5%)235/1131 (20.8%)1.000
Type of imaging0.010
  MRI42/165 (25.5%)994/1544 (64.4%)
  CT123/165 (74.5%)550/1544 (35.6%)
Treatment
 IVT use71/165 (43.0%)779/1574 (49.5%)0.120
 Time from onset of symptoms to IVT needle (min)165 (113–210), N=39/71120 (83–165), N=437/7790.003
 Time from onset of symptoms to admission in stroke center (min)228 (IQR 121–369), N=132143 (71–245), N=1380<0.001
 Time from onset of symptoms to groin puncture (min)300 (IQR 211–480), N=133225 (165–315), N=1346<0.001
  • ACLVO, anterior circulation large-vessel occlusion; BAO, basilar artery occlusion; IVT, intravenous thrombolysis; NIHSS, National Institutes of Health Stroke Scale; NOAC, non-vitamin K antagonist oral anticoagulants;TOAST, Trial of ORG 10172 in Acute Stroke Treatment; VKA, vitamin K antagonist.Difference in numbers of observations and total numbers of patients in each group due to missing data items.