Table 4

Univariate and multivariate regression modeling of patient variables that predict clinical outcome in the total study population

VariableUnivariateMultivariate
OR (95% CI)P valueOR (95% CI)P value
Age1.05 (1.02 to 1.07)<0.0011.03 (1.00 to 1.07)0.04
Gender (male)0.67 (0.37 to 1.22)0.19
Onset to arrival0.98 (0.90 to 1.07)0.63
Onset to imaging0.98 (0.91 to 1.04)0.45
Arrival to imaging0.99 (0.85 to 1.13)0.83
Imaging to GP0.86 (0.69 to 1.09)0.21
Onset to tPA0.74 (0.51 to 1.07)0.11
Onset to GP0.96 (0.89 to 1.04)0.34
GP to revascularization1.39 (0.89 to 2.53)0.21
Onset to revascularization0.98 (0.89 to 1.07)0.32
CT1.18 (0.64 to 2.18)0.60--
CTA0.85 (0.46 to 1.56)0.60
CTP0.58 (0.31 to 1.09)0.09
MRA0.41 (0.02 to 10.75)0.54
Pre-procedure mRS1.40 (1.14 to 1.74)0.0021.25 (0.97 to 1.62)0.09
Pre-procedure NIHSS1.10 (1.05 to 1.16)<0.0011.03 (0.95 to 1.10)0.05
IA tPA0.76 (0.42 to 1.36)0.36----
Passes with primary technique1.27 (1.03 to 1.59)0.031.17 (0.85 to 1.65)0.35
Final TICI score0.70 (0.51 to 0.94)0.020.86 (0.55 to 1.32)0.48
Post-intervention ICH4.13 (1.77 to 10.14)0.0014.49 (0.99 to 25.55)0.06
Post-procedure mRS3.36 (2.57 to 4.52)<0.001
Post-procedure NIHSS1.25 (1.18 to 1.33)<0.001
  • Threshold for statistical significance was set at p<0.05.

  • CTA, CT angiography; CTP, CT perfusion; GP, groin puncture; ICH, intracranial hemorrhage; MRA, MR angiography; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; TICI, Thrombolysis in Cerebral Infarction; tPA, tissue plasminogen activator.