Procedural details and clinical outcomes of EVT for AIS patients in pre-pandemic and pandemic groups
Pre-pandemic group | Pandemic group | OR (95% CI) | P value | |
mTICI 2b–3, n (%) | 30 (88.2) | 18 (85.7) | 0.971 (0.785 to 1.203) | 1.000 |
Local anesthesia, n (%) | 23 (67.6) | 18 (85.7) | 1.267 (0.947 to 1.695) | 0.240 |
ADAPT as the first choice, n (%) | 10 (29.4) | 9 (42.9) | 1.457 (0.711 to 2.987) | 0.308 |
Solumbra as the first choice, n (%) | 18 (52.9) | 10 (47.6) | 0.899 (0.519 to 1.558) | 0.701 |
Stent retriever as the first choice, n (%) | 3 (8.8) | 0 | NA | 0.279 |
Rescue treatment, n (%) | 10 (29.4) | 5 (23.8) | 0.810 (0.321 to 2.043) | 0.650 |
Balloon angioplasty, n (%) | 4 (11.8) | 4 (19.0) | 1.619 (0.453 to 5.792) | 0.464 |
Stent placement, n (%) | 8 (23.5) | 1 (4.8) | 0.202 (0.027 to 1.505) | 0.146 |
Hospital arrival to puncture time, median (IQR), min | 125.5 (113–153) | 174 (139–204) | NA | 0.002 |
Puncture to reperfusion time, median (IQR), min | 40.5 (28.5–55.5) | 32 (28–43) | NA | 0.231 |
Hospital arrival to reperfusion time, median (IQR), min | 172 (148–218.5) | 213 (177–256) | NA | 0.047 |
Onset to reperfusion time, median ±SD, min | 478.28±160.6 | 511.68±213.54 | NA | 0.529 |
24 hours NIHSS score, median (IQR) | 14 (6–40) | 10 (6–40) | NA | 0.380 |
72 hours NIHSS score, median (IQR) | 8 (5–14) | 8 (4–21) | NA | 0.675 |
Overall adverse events, n (%) | 12 (35.3) | 6 (28.6) | 0.810 (0.358 to 1.829) | 0.606 |
Subarachnoid hemorrhage, n (%) | 3 (8.8) | 4 (19.0) | 2.159 (0.535 to 8.707) | 0.408 |
All intracranial hemorrhage, n (%) | 9 (26.5) | 3 (14.3) | 0.540 (0.165 to 1.770) | 0.467 |
Hemorrhagic transformation, n (%) | 7 (20.6) | 2 (9.5) | 0.463 (0.106 to 2.021) | 0.482 |
ADAPT, a direct aspiration first pass technique; AIS, acute ischemic stroke; EVT, endovascular thrombectomy; IQR, interquartile range (25–75%); mTICI, modified Thrombolysis In Cerebral Infarction; NA, not applicable.