Patient characteristics
| Baseline characteristics | Vessel recanalization | Persistent vessel occlusion | Group comparison P value |
| Admission parameter | |||
| Subjects, n (%) | 50 (50) | 50 (50) | |
| Age in years, mean (SD) | 68 (13) | 75 (12) | 0.01 |
| Female sex, n (%) | 15 (29) | 20 (40) | 0.35 |
| Admission NIHSS, mean (SD) | 16.4 (3.6) | 19.0 (5.0) | 0.007 |
| ASPECTS, median (IQR) | 5 (4–5) | 4 (3–5) | 0.01 |
| Ischemic core volume, mL (SD) | 48.9 (28.5) | 65.2 (40.4) | 0.06 |
| Time from onset to imaging in hours, median (IQR) | 3.9 (2.3–4.5) | 3.5 (2.5–4.5) | 0.99 |
| Administered intravenous lysis, n (%) | 28 (56) | 25 (50) | 0.62 |
| Net water uptake, mean % (SD) | 9.6 (5.1) | 11.0 (4.5) | 0.19 |
| Collateral score, median (IQR) | 1 (0–2) | 1 (0–1) | 0.04 |
| Mechanical thrombectomy, n (%) | 50 (100) | 24 (48) | <0.001 |
| Follow-up endpoints | |||
| Delta net water uptake, mean % (SD) | 7.2 (5.6) | 15.0 (7.7) | <0.001 |
| Follow-up infarct volume in mL, median (IQR) | 107 (76–138) | 156 (126–186) | 0.02 |
| Parenchymal hemorrhage, n (%) | 3 (6) | 3 (6) | 1.00 |
| Malignant infarctions, n (%) | 13 (26) | 23 (46) | 0.06 |
| Mortality, n (%) | 9 (18) | 24 (48) | <0.001 |
| mRS, median (IQR) | 4 (2.5–5) | 5 (5–6) | <0.001 |
| mRS 0–2, n (%) | 12 (24) | 1 (2) | <0.001 |
| mRS 3–4, n (%) | 13 (26) | 8 (16) | 1.0 |
| mRS 5–6, n (%) | 25 (50) | 41 (82) | <0.001 |
ASPECTS, Alberta Stroke Program Early CT Score ; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale.