| Female (N) | Male (N) | Odds ratios | Lower limits- Upper limits | P-value | ||
|---|---|---|---|---|---|---|
| Discharge to home | ||||||
| Medically treated group (N= 44,473) | 30,970 | 13,503 | ||||
| Univariate model (female vs. male) | 1.82 | 1.66–2.00 | <0.001 | |||
| Multivariate model (female vs. male) | 1.03 | 0.91–1.16 | 0.69 | |||
| EVT treated group (N= 2,065) | 1,384 | 681 | ||||
| Univariate model (female vs. male) | 1.02 | 0.68–1.51 | 0.94 | |||
| Multivariate model (female vs. male) | 0.70 | 0.40–1.24 | 0.22 | |||
| In-hospital mortality | ||||||
| Medically treated group (N= 44,473) | 30,970 | 13,503 | ||||
| Univariate model (female vs. male) | 0.45 | 0.35–0.57 | <0.001 | |||
| Multivariate model (female vs. male) | 0.78 | 0.57–1.06 | 0.11 | |||
| EVT treated group (N= 2,065) | 1,384 | 681 | ||||
| Univariate model (female vs. male) | 1.64 | 0.83–3.24 | 0.15 | |||
| Multivariate model (female vs. male) | 1.60 | 0.62–4.11 | 0.33 | |||
--Multivariate model: Patient-level characteristics including Age, gender, Charlson comorbidity index, race, hematological conditions, CNS infections, brain tumors, any cancers, inflammatory conditions, traumatic brain injuries, DM, hypertension, drug abuse, smoking, EtOH abuse, seizures disorders, coma, cerebral edema, hydrocephalus, migraine, intracranial hemorrhage, ischemic stroke, ventriculostomy, invasive mechanical ventilation, tracheostomy and PEG tube.
--Hematological conditions, including sickle cell disorders, coagulation, hemorrhagic disorders, polycythemia, hypersplenism, and diseases of the spleen.
--Systemic inflammatory disease which includes systemic lupus erythematosus, rheumatoid disorders and other related conditions, and other connective tissue disorders.
--CNS infections include meningitis, encephalitis, other CNS infection and poliomyelitis
--Charlson comorbidity index: The severity of co-morbid conditions was defined using the Charlson-Deyo Co-morbidity Index (CCI). CCI is an established measure to quantify the burden co-morbid conditions; the scores range from 0 to 33 with a higher score indicating a greater burden of concomitant diseases. Derived from: Roffman CE, Buchanan J, Allison GT. Charlson Comorbidities Index. Journal of physiotherapy. 2016;62(3):171.