Table 2

Independent predictors for late EVT eligibility according to trial and liberal criteria in late-arriving patients with AIS (n=925)

PredictorsTrial (DAWN and/or DEFUSE-3) eligibilityLiberal eligibility
OR (95% CI)P valueOR (95% CI)P value
Pre-stroke mRS0.64 (0.48 to 0.86)<0.01
Hypercholesterolemia2.79 (1.43 to 5.46)<0.01
NIHSS1.12 (1.07 to 1.16)<0.01
Eye deviation2.94 (1.44 to 6.01)<0.012.06 (1.08 to 3.92)0.03
Visual field defects2.75 (1.32 to 5.70)0.01
Hemiparesis4.72 (1.10 to 20.30)0.04
LPGH-to-arrival time0.95 (0.91 to 0.98)<0.010.94 (0.91 to 0.97)<0.01
  • Only significant results are shown. The model for liberal eligibility also included the variables known onset, statin use, smoking, and systolic blood pressure on admission, which were included to obtain a good calibration of the model according to the Hosmer–Lemeshow test. The time unit for LPGH-to-arrival time is 30 min.

  • AIS, acute ischemic stroke; EVT, endovascular treatment; LPGH, last proof of good health; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale.