Study characteristics
| Study characteristic | Studies, n | Patients, n* |
| Article type | ||
| Full | 39 | 2452 |
| Abstract | 2 | 162 |
| Study design | ||
| Retrospective case series | 28 | 1881 |
| Prospective case series | 7 | 428 |
| Retrospective comparative study (non-randomized) | 6 | 305 |
| Flow-diverter device | ||
| Pipeline† | 29 | 1972 |
| Surpass† | 2 | 23 |
| DERIVO | 1 | 24 |
| FRED | 1 | 20 |
| Pipeline Shield | 1 | 50 |
| Silk | 1 | 246 |
| Mixed | 6 | 279 |
| Method for occlusion verification | ||
| Core lab/independent review | 14 | 678 |
| Site reported/not specified | 27 | 1936 |
| Method for adverse events verification | ||
| Independent review/clinical events committee | 8 | 857 |
| Site reported/not specified | 33 | 1757 |
| Region | ||
| North America | 20 | 1230 |
| Europe | 13 | 452 |
| Asia-Pacific | 2 | 198 |
| Latin America | 2 | 362 |
| Multi-continental | 4 | 372 |
| Percent unruptured category | ||
| 90–<95% | 7 | 836 |
| 95–<100% | 5 | 374 |
| 100% | 25 | 1223 |
| Not reported‡ | 4 | 181 |
| Aneurysm size category | ||
| Small: mean/median <7 mm or exclusively small size | 16 | 1515 |
| Medium: mean/median 7–12 mm | 22 | 789 |
| Mean/median not reported§ | 3 | 310 |
| Percent ICA category | ||
| 90–<95% | 10 | 413 |
| 95–<100% | 4 | 545 |
| 100% | 27 | 1656 |
*Two studies did not report number of eligible patients: 57 aneurysms in the subset of eligible patients18 and 118 aneurysms in the subset of eligible patients.19
†Commercially available in USA at the time the review was conducted.
‡Unruptured percentage determined to be at least 90% per selection criteria, but exact number not extractable.
§Mean/median aneurysm size determined to be ≤12 mm per selection criteria, but exact number not extractable.
ICA, internal carotid artery.