Subanalysis based on antihypertensive use in the first 24 hours, history of hypertension, admission systolic blood pressure, and reperfusion status
| Groups | Model (N) | OR (95% CI) | P value |
| Anti-hypertensive drug use | Model 1 (548) | 0.98 (0.97 to 0.99) | 0.034 |
| Model 2 (513) | 0.98 (0.97 to 1) | 0.045 | |
| No anti-hypertensive drug use | Model 1 (459) | 0.98 (0.97 to 0.99) | 0.014 |
| Model 2 (420) | 0.98 (0.96 to 0.99) | 0.006 | |
| Hypertension | Model 1 (853) | 0.99 (0.98 to 1.002) | 0.116 |
| Model 2* (812) | 0.99 (0.98 to 1.003) | 0.156 | |
| No hypertension | Model 1 (506) | 0.98 (0.97 to 1.001) | 0.071 |
| Model 2* (466) | 0.98 (0.97 to 1.001) | 0.076 | |
| Admission SBP >140 | Model 1 (678) | 0.97 (0.96 to 0.99) | 0.005 |
| Model 2 (637) | 0.97 (0.95 to 0.99) | 0.008 | |
| Admission SBP ≤140 | Model 1 (681) | 0.98 (0.97 to 0.99) | 0.007 |
| Model 2 (641) | 0.97 (0.96 to 0.99) | 0.001 | |
| mTICI 3 | Model 1 (728) | 0.98 (0.97 to 0.99) | 0.010 |
| Model 2** (691) | 0.98 (0.97 to 0.98) | 0.014 | |
| mTICI 2b | Model 1 (630) | 0.99 (0.98 to 1.008) | 0.514 |
| Model 2** (588) | 0.99 (0.98 to 1.007) | 0.406 | |
| NIHSS score <16 | Model 1 (772) | 0.98 (0.97 to 0.99) | 0.002 |
| Model 2** (682) | 0.98 (0.97 to 0.99) | 0.005 | |
| NIHSS score ≥16 | Model 1 (627) | 1.001 (0.98 to 1.01) | 0.89 |
| Model 2** (589) | 1.001 (0.98 to 1.01) | 0.86 |
Model 1 adjusted for center, age, admission NIHSS.
Model 2 adjusted for age, female, Caucasian race, admission ASPECTS, diabetes, hypertension, atrial fibrillation, admission NIHSS, IV tPA, onset-to-groin time, etiology, and complete recanalization (mTICI3).
ASPECTS, Alberta Stroke Program Early CT Score; mTICI, modified Thrombolysis in Cerebral Infarction ; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure; tPA, tissue plasminogen activator.