Clinical characteristics and outcomes of patients who underwent mechanical thrombectomy under general anesthesia vs monitored anesthesia care
| General anesthesia (n=241)* | Monitored anesthesia care (n=215) | P-value† | |
| Age, median (IQR) | 70 (58–79) | 73 (63–82) | 0.02 |
| Females, n (%) | 104 (43.2%) | 105 (48.8%) | 0.224 |
| White, n (%) | 160 (66.4%) | 149 (69.3%) | 0.507 |
| LKN to hospital door, median (IQR) | 283 (100–485) | 255 (120–517) | 0.791 |
| Admission NIHSS, median (IQR) | 16 (10–22) | 15 (10–20) | 0.226 |
| IV-tPA, n (%) | 110 (45.6%) | 73 (34%) | 0.011 |
| ASPECTS, median (IQR)‡ | 8 (7–10) | 9 (7–10) | 0.305 |
| Posterior circulation, n (%) | 31 (12.9%) | 15 (7%) | 0.037 |
| Door to groin, median (IQR) | 92 (62–136) | 67 (35–112) | <0.001 |
| LKN to groin, median (IQR) | 355 (213–620) | 335 (191–687) | 0.564 |
| Number of passes, median (IQR) | 2 (1–3) | 2 (1–3) | 0.138 |
| Achieved successful reperfusion, n (%) | 198 (82.2%) | 181 (84.2%) | 0.564 |
| Procedure duration, median (IQR) | 47 (27–76) | 32 (19–56) | <0.001 |
| Door to reperfusion, median (IQR) | 138 (92–188) | 100 (64–156) | <0.001 |
| Length of stay, median (IQR) | 6 (3–11) | 5 (3–9) | 0.111 |
| DC mRS, median (IQR)§ | 4 (3–6) | 4 (2–5) | 0.008 |
| Functional independence on discharge (mRS 0–2), n (%)§ | 45 (24.5%) | 51 (35.4%) | 0.03 |
| sICH, n (%) | 17 (7.1%) | 11 (5.1%) | 0.39 |
*Excluded two patients who required intra-procedural intubation.
†Calculated using chi-suare test for categorical variables and Wilcoxon test for the continuous variables.
‡Only for patients with anterior circulation occlusion.
§Missing for 128 patients (57 in the intubated group and 71 in the un intubated group).
ASPECTS, Alberta Stroke Program Early CT score; COVID, coronavirus disease of 2019; DC, discharge; IV-tPA, intravenous tissue plasminogen activator; LKN, last known normal; mRS, modified Rankin Scale; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institute of Health Stroke Scale; sICH, symptomatic intracerebral hematoma.