Clinical characteristics and outcomes of patients in high and low COVID-19 counties
| Thrombectomy patients in high COVID-19 burden counties (n=104) | Thrombectomy patients in low COVID-19 counties (n=354) | P-value* | |
| Age, median (IQR) | 70 (58–78) | 72 (60–80) | 0.219 |
| Females, n (%) | 46 (44.2%) | 164 (46.3%) | 0.706 |
| White, n (%) | 71 (68.3%) | 239 (67.5%) | 0.885 |
| LKN to hospital door, median (IQR) | 286 (144–639) | 255 (105–490) | 0.262 |
| Admission NIHSS, median (IQR) | 15 (11–20) | 16 (10–21) | 0.491 |
| IV-tPA, n (%) | 29 (27.9%) | 155 (43.8%) | 0.004 |
| ASPECTS, median (IQR)† | 9 (8–10) | 8 (7–10) | 0.063 |
| Posterior circulation, n (%) | 8 (7.7%) | 38 (10.7%) | 0.364 |
| Intubation, n (%) | 38 (36.5%) | 203 (57.3%) | <0.001 |
| Door to groin, median (IQR) | 68 (36–123) | 85 (54–127) | 0.054 |
| LKN to groin, median (IQR) | 350 (195–686) | 352 (200–651) | 0.529 |
| Number of passes, median (IQR) | 2 (1–3) | 2 (1–3) | 0.395 |
| mTICI ≥2 b, n (%) | 83 (79.8%) | 298 (84.2%) | 0.294 |
| Procedure duration, median (IQR) | 35 (23–62) | 41 (25–69) | 0.177 |
| Door to reperfusion, median (IQR) | 111 (60–188) | 127 (79–176) | 0.221 |
| Length of stay, median (IQR) | 5 (3–10) | 6 (3–10) | 0.387 |
| DC mRS, median (IQR)‡ | 4 (2–6) | 4 (2–5) | 0.713 |
| Functional independence at discharge (mRS 0–2), n (%)‡ | 23 (30.7%) | 73 (28.7%) | 0.747 |
| sICH, n (%) | 9 (8.7%) | 19 (5.4%) | 0.219 |
*Calculated using chi-square test for categorical variables and Wilcoxon test for the continuous variables.
†Only for patients with anterior circulation occlusion.
‡Missing for 130 patients.
ASPECTS, Alberta Stroke Program Early CT score; COVID-19, coronavirus disease of 2019; DC, discharge; IV-tPA, intravenous tissue plasminogen activator; LKN, last known normal; mRS, modified Rankin Scale; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institute of Health Stroke Scale; sICH, symptomatic intracerebral hematoma.