Table 1

Characteristics and reported outcomes for studies included in the systematic review

StudyDesignImaging modalityLarge core definitionmRS 0–2Symptomatic ICHMortality
EVTMM onlyEVTMM onlyEVTMM only
Sarraj et al. (2019)PCCT and CT PerfusionCT ASPECTS 0–5, ischemic core ≥50cc19/62 (31%)6/43 (14%)8/62 (13%)3/43 (7%)18/62 (29%)18/43 (42%)
Kakita et al. (2019)PCCT/DWIASPECTS 0–534/172 (20%)14/332 (4%)6/163 (4%)14/287 (5%)24/172 (14%)89/332 (27%)
Chen et al. (2018)RCCT Perfusion/DWIIschemic core ≥70cc9/28 (32%)7/76 (9%)3/28 (11%)7/74 (9%)7/28 (25%)26/76 (34%)
Campbell et al. (2018)PMACT Perfusion/DWIIschemic core ≥70cc9/48 (19%)7/61 (11%)1/48 (2%)5/62 (8%)14/48 (29%)27/61 (44%)
Mourand et al. (2018)RCDWIASPECTS 0–518/60 (30%)1/48 (2%)3/60 (5%)3/48 (6%)15/60 (25%)23/48 (48%)
Roman et al. (2018)PMACT/DWIASPECTS 0–530/109 (28%)17/116 (15%)15/104 (14%)4/111 (4%)18/57 (32%)25/70 (36%)
Jiang et al. (2018)16 RCNot describedASPECTS 0–56/36 (17%)0/53 (0%)7/36 (19%)4/53 (8%)12/26 (46%)23/53 (43%)
Rebello et al. (2017)MCCCT PerfusionIschemic core ≥50cc6/24 (25%)0/23 (0%)NRNR7/24 (29%)11/23 (48%)
Yoo et al. (2016)SACT/DWIASPECTS 0–41/11 (9%)0/19 (0%)1/11 (9%)1/19 (5%)4/11 (36%)6/19 (32%)
Goyal et al. (2016)PMACT/DWIASPECTS 0–513/57 (23%)9/64 (14%)NRNR17/57 (30%)22/64 (34%)
Bracard et al. (2016)SACT/DWIASPECTS 0–49/35 (26%)8/22 (36%)NRNRNRNR
Borst et al. (2015)SACT PerfusionIschemic core ≥70cc1/13 (8%)0/21 (0%)NRNR5/13 (38%)7/21 (33%)
  • MCC, matched case-control study; NR, not reported; PC, prospective cohort; PMA, pooled patient level meta-analysis of RCTs; RC, retrospective cohort; SA, sub-analysis of a RCT.