Demographic data | All subjects (n=183) | MCA M1 (n=126) | MCA M2 (n=57) | P value |
Age at enrollment, years | ||||
Mean (SD) | 68.2 (12.9) | 66.9 (13.1) | 71.2 (12.0) | 0.0330 |
Median | 70 | 69 | 75 | |
Min to max | 20 to 86 | 23 to 85 | 20 to 86 | |
≥75, N (%) | 74 (40.4) | 45 (35.7) | 29 (50.9) | 0.0529 |
<75, N (%) | 109 (59.6) | 81 (64.3) | 28 (49.1) | |
Sex, N (%) | ||||
Male | 87 (47.5) | 57 (45.2) | 30 (52.6) | 0.3537 |
Female | 96 (52.5) | 69 (54.8) | 27 (47.4) | |
NIHSS score at presentation | ||||
Mean (SD) | 15.42 (4.42) | 15.90 (4.41) | 14.37 (4.31) | 0.0507 |
Median | 16 | 16 | 14 | |
Q1 to Q3 | 12 to 19 | 12 to 19 | 12 to 18 | |
Min to max | 7 to 26 | 8 to 26 | 7 to 23 | |
Baseline ASPECTS | ||||
N | 168 | 117 | 51 | |
Mean (SD) | 9.38 (1.16) | 9.38 (1.22) | 9.37 (1.00) | 0.3723 |
Median | 10.00 | 10.00 | 10.00 | |
Q1 to Q3 | 9.00 to 10.00 | 9.00 to 10.00 | 9.00 to 10.00 | |
Min to max | 4.00 to 10.00 | 4.00 to 10.00 | 5.00 to 10.00 | |
Pre-stroke mRS score, N (%) | ||||
0 | 139 (76.0) | 96 (76.2) | 43 (75.4) | 0.8983 |
1 | 43 (23.5) | 29 (23.0) | 14 (24.6) | |
2 | 1 (0.5) | 1 (0.8) | 0 | |
Occlusion side, left, N (%) | 87 (47.5) | 57 (45.2) | 30 (52.6) | 0.3537 |
Symptom onset or LKW to arterial puncture, min | ||||
N | 140 | 95 | 45 | |
Mean (SD) | 201.59 (77.28) | 198.72 (76.26) | 207.64 (79.93) | 0.5251 |
Median | 195 | 187 | 214 | |
Hypertension, N (%) | 127 (69.4) | 85 (67.5) | 42 (73.7) | 0.3975 |
Diabetes mellitus, N (%) | 37 (20.2) | 25 (19.8) | 12 (21.1) | 0.8501 |
Atrial fibrillation, N (%) | 72 (39.3) | 47 (37.3) | 25 (43.9) | 0.4003 |
Hyperlipidemia, N (%) | 80 (43.7) | 50 (39.7) | 30 (52.6) | 0.1020 |
Smoking, N (%) | 48 (26.2) | 36 (28.6) | 12 (21.1) | 0.2843 |
Previous MI/CAD, N (%) | 39 (21.3) | 30 (23.8) | 9 (15.8) | 0.2199 |
Previous stroke, N (%) | 33 (18.0) | 21 (16.7) | 12 (21.1) | 0.4748 |
Intravenous tPA failure, N (%) | 123 (67.2) | 85 (67.5) | 38 (66.7) | 0.9157 |
For continuous variables, p values are generated using a t-test, with a Satterthwaite approximation in cases of unequal variances.
For ordinal variables (NIHSS score at presentation, baseline ASPECTS), p values are generated using the Wilcoxon rank-sum test.
ASPECTS, baseline Alberta Stroke Program Early CT score; CAD, coronary artery disease; IA, intra-arterial; IV, intravenous; LKW, last known well; MCA, middle cerebral artery; MI, myocardial; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale/Score; tPA, tissue plasminogen activator.